Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.59 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.58 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.58 |
| ▸ | DNM2 | P50570 | 1/20 | 0.58 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PHGDH | O43175 | 1/20 | 0.54 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2031092 | 0.93 | KCNK2 (0.64) | SERPINE1KCNK2KCNK10ERO1AKMT2A | |
| SCHEMBL13802484 | 0.87 | HTT (0.74) | SERPINE1KCNK2KCNK10ERO1AKMT2A | |
| SCHEMBL15668406 | 0.85 | MAPT (0.66) | KMT2AMEN1PKMHTTSMN1; SMN2 | |
| SCHEMBL2024935 | 0.84 | MEN1 (0.71) | ERO1AKMT2AMEN1PKMAKR1C4 | |
| SCHEMBL1308714 | 0.83 | MEN1 (0.76) | SERPINE1KCNK2KCNK10KMT2AMEN1 | |
| SCHEMBL2269733 | 0.82 | ACLY (0.59) | SERPINE1KCNK2KCNK10DNM2ERO1A | |
| SCHEMBL13802483 | 0.82 | WDR5 (0.60) | SERPINE1KCNK2KCNK10ERO1AKMT2A | |
| SCHEMBL7787033 | 0.81 | KMT2A (0.72) | KCNK2KCNK10DNM2ERO1AKMT2A | |
| SCHEMBL10981544 | 0.79 | MAPT (0.69) | KMT2AMEN1HTTSMN1; SMN2HPGD | |
| SCHEMBL6716445 | 0.79 | ALDH1A1 (0.60) | KMT2AMEN1PKMNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | SERPINE1 1045/4885KCNK2 2183/4885KCNK10 2814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.