Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.60 |
| ▸ | PYGL | P06737 | 2/20 | 0.57 |
| ▸ | PYGM | P11217 | 2/20 | 0.57 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2031092 | 0.87 | KCNK2 (0.64) | KMT2AMEN1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL2024935 | 0.86 | MEN1 (0.71) | KMT2AMEN1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6784799 | 0.83 | TERT (0.71) | KMT2AMEN1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL13802485 | 0.81 | SERPINE1 (0.59) | KMT2AMEN1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL13802484 | 0.81 | HTT (0.74) | KMT2AMEN1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL8044197 | 0.80 | DHODH (0.79) | KMT2AMEN1NPC1RAB9ADHODH | |
| SCHEMBL7380312 | 0.80 | MPO (0.62) | KMT2AMEN1AKR1C3AKR1C2NPC1 | |
| SCHEMBL8337049 | 0.80 | MEN1 (0.68) | KMT2AMEN1ERO1ANPC1RAB9A | |
| SCHEMBL1307456 | 0.80 | GRIK1 (0.67) | KMT2AMEN1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL2274133 | 0.79 | MEN1 (0.64) | KMT2AMEN1PYGLPYGMERO1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |