Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.59 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.59 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.59 |
| ▸ | CFD | P00746 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18076580 | 0.80 | PTGER4 (0.61) | PTGER4PTGER3PTGER1PTGER2CFD | |
| SCHEMBL13802494 | 0.79 | PTGER1 (0.57) | PTGER4PTGER3PTGER1PTGER2CFD | |
| SCHEMBL4089867 | 0.79 | PTGER1 (0.61) | PTGER4PTGER3PTGER1PTGER2CFD | |
| SCHEMBL28451933 | 0.78 | PTGER4 (0.60) | PTGER4PTGER3PTGER1PTGER2CFD | |
| SCHEMBL27711541 | 0.77 | PTGER4 (0.55) | PTGER4PTGER3PTGER1PTGER2CFD | |
| SCHEMBL3908596 | 0.77 | CFD (0.66) | CFDFFAR1ENPP2FFAR4MRGPRX4 | |
| SCHEMBL7710805 | 0.76 | PTGER4 (0.55) | PTGER4PTGER3PTGER1PTGER2CFD | |
| SCHEMBL962238 | 0.76 | FFAR1 (0.60) | FFAR1FFAR4MRGPRX4MAOB | |
| SCHEMBL7743316 | 0.75 | MRGPRX4 (0.60) | PTGER1MRGPRX4MAOBNR4A2 | |
| SCHEMBL4941479 | 0.74 | AKR1B1 (0.43) | PTGER4PTGER3PTGER1PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553867-B2 | Furan or thiophene derivative and medicinal use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20060100261-A1 | Furan or thiopene derivative and medicinal use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED INTELLECTUAL PROPERTY DEPARTMENT (JP) | 2006-05-11 | — | — | US | disclosed |
| EP-1535915-A1 | FURAN OR THIOPHENE DERIVATIVE AND MEDICINAL USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2005-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100261-A1 | Furan or thiopene derivative and medicinal use thereof | TXN2, CYP11B2, CYP11B1 | PTGER4 115/4885PTGER3 117/4885PTGER1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.