SCHEMBL13804530

SCHEMBL13804530

CNC(=O)Nc1cccc(O)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
RECQL P46063 2/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
TDP1 Q9NUW8 3/20 0.50
POLB P06746 1/20 0.50
TRPV1 Q8NER1 2/20 0.43
LMNA P02545 3/20 0.42
GAA P10253 3/20 0.42
MAPT P10636 2/20 0.42
HTT P42858 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
IKBKB O14920 1/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ADAMTS4 O75173 1/20 0.41
EGFR P00533 1/20 0.41
FYN P06241 1/20 0.41
MMP2 P08253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7254971 0.90 ALDH1A1 (0.72) ALDH1A1RECQLSMN1; SMN2TDP1POLB
SCHEMBL7094650 0.84 ALDH1A1 (0.76) ALDH1A1RECQLSMN1; SMN2TDP1POLB
SCHEMBL19004112 0.80 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2TDP1POLBGAA
SCHEMBL14003501 0.79 ALDH1A1 (1.00) ALDH1A1RECQLSMN1; SMN2TDP1POLB
SCHEMBL14012050 0.76 GAA (0.43) ALDH1A1TRPV1LMNAGAAMAPT
SCHEMBL17715571 0.74 HPGD (0.52) ALDH1A1RECQLSMN1; SMN2TDP1POLB
Pyrogallol SCHEMBL28029063 0.74 ALDH1A1 (0.48) ALDH1A1RECQLSMN1; SMN2TDP1POLB
SCHEMBL9313065 0.74 CA1 (0.46) ALDH1A1RECQLTDP1LMNAGAA
SCHEMBL28416832 0.74 ALDH1A1 (0.87) ALDH1A1RECQLSMN1; SMN2TDP1POLB
SCHEMBL12556433 0.73 TERT (0.66) ALDH1A1SMN1; SMN2LMNAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7553796-B2 Phenol compound, reversible thermosensitive recording medium, reversible thermosensitive recording label, reversible thermosensitive recording member, image-processing apparatus and image-processing method RICOH COMPANY, LTD. (JP) 2009-06-30 US disclosed
US-20080242539-A1 Phenol Compound, Reversible Thermosensitive Recording Medium, Reversible Thermosensitive Recording Label, Reversible Thermosensitive Recording Member, Image-Processing Apparatus and Image-Processing Method RICOH COMPANY, LTD. (JP) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242539-A1 Phenol Compound, Reversible Thermosensitive Recording Medium, Reversible Thermosensitive Recording Label, Reversible Thermosensitive Recording Member, Image-Processing Apparatus and Image-Processing Method TRPV1, TRPV6, TRPA1 ALDH1A1 638/4885RECQL 2020/4885SMN1; SMN2 3479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.