Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 5/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13851545 | 0.82 | MAOA (0.63) | MAOAMAOBMAPT | |
| SCHEMBL9000108 | 0.80 | PTPRF (0.46) | PTPRFMAOAMAOBSMN1; SMN2MAPT | |
| SCHEMBL4006708 | 0.78 | MAOA (0.40) | PTPRFCYP19A1PARP1MAOAADORA3 | |
| SCHEMBL3999560 | 0.76 | CYP19A1 (0.51) | CYP19A1PARP1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL1072092 | 0.73 | SMN1; SMN2 (0.61) | PTPRFMAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL13115609 | 0.72 | ACHE (0.68) | CYP19A1PARP1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL29793269 | 0.71 | MAOB (0.47) | CYP19A1PARP1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL78594 | 0.71 | MAOB (0.47) | CYP19A1PARP1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL28725626 | 0.70 | CYP19A1 (0.54) | CYP19A1PARP1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL28725627 | 0.70 | CYP19A1 (0.54) | CYP19A1PARP1MAOAMAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071799-A1 | PROCESS FOR THE SYNTHESIS OF 4-BENZOFURANCARBOXYLIC ACID | ZACH SYSTEM (FR) | 2009-06-11 | — | — | WO | disclosed |
| US-20090131688-A1 | METHOD FOR THE SYNTHESIS OF 4-BENZOFURAN-CARBOXYLIC ACID | ZACH SYSTEM (FR) | 2009-05-21 | — | — | US | disclosed |
| US-20090131688-A1 | METHOD FOR THE SYNTHESIS OF 4-BENZOFURAN-CARBOXYLIC ACID | ZACH SYSTEM (FR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131688-A1 | METHOD FOR THE SYNTHESIS OF 4-BENZOFURAN-CARBOXYLIC ACID | COASY, HSD17B12, ALDH18A1 | PTPRF 4461/4885CYP19A1 7/4885PARP1 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.