Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRF | P10586 | 1/20 | 0.46 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13808564 | 0.80 | PTPRF (0.47) | PTPRFSMN1; SMN2MAOAMAOBMAPT | |
| SCHEMBL28847777 | 0.73 | LDHA (0.53) | MAOBLDHAMAPT | |
| SCHEMBL1072092 | 0.72 | SMN1; SMN2 (0.61) | PTPRFSMN1; SMN2MAOAMAOBMAPT | |
| SCHEMBL28968289 | 0.71 | AADAT (0.36) | PTPRFAADATSMN1; SMN2CA1CA2 | |
| SCHEMBL28968292 | 0.71 | AADAT (0.36) | PTPRFAADATSMN1; SMN2CA1CA2 | |
| SCHEMBL3890561 | 0.70 | SMARCA2 (0.36) | MAPK14NOTUMLDHANSD2 | |
| SCHEMBL87504 | 0.69 | MAOB (0.47) | MAOAMAOBMAPTNSD2 | |
| SCHEMBL29504833 | 0.69 | MAOB (0.47) | MAOAMAOBMAPTNSD2 | |
| SCHEMBL8558933 | 0.69 | ACHE (0.40) | AADATMAPK14NOTUMMAPTNSD2 | |
| SCHEMBL20539615 | 0.69 | ACHE (0.40) | AADATMAPK14NOTUMMAPTNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730468-A1 | MEDICINAL ACTIVITY OF ASPARTAME | Messadek, Jallal (BE) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014486-A1 | MEDICINAL ACTIVITY OF ASPARTAME | MESSADEK, JALLAL (BE) | 1995-06-01 | — | — | WO | disclosed |