Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.45 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27579381 | 0.91 | LTA4H (0.59) | LTA4HKIF11NR3C1PGRAR | |
| SCHEMBL11527555 | 0.87 | KIF11 (0.51) | P2RY1KIF11MAPTL3MBTL1CETP | |
| SCHEMBL9798371 | 0.87 | LTA4H (0.54) | LTA4HKIF11NR3C1PGRAR | |
| SCHEMBL9546526 | 0.85 | L3MBTL1 (0.55) | LTA4HKIF11NR3C1PGRAR | |
| SCHEMBL9589615 | 0.82 | LTA4H (0.53) | LTA4HKIF11NR3C1PGRAR | |
| SCHEMBL15635197 | 0.82 | PPARG (0.55) | LTA4HP2RY1KIF11NR3C1PGR | |
| SCHEMBL3553556 | 0.82 | LTA4H (0.52) | LTA4HKIF11NR3C1PGRAR | |
| SCHEMBL4043144 | 0.82 | LTA4H (0.53) | LTA4HKIF11NR3C1PGRAR | |
| SCHEMBL5542591 | 0.82 | LTA4H (0.52) | LTA4HKIF11NR3C1PGRAR | |
| SCHEMBL476378 | 0.82 | ALDH1A1 (0.66) | LTA4HKIF11NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072498-A1 | N-PHENYLOXAMIDIC ACID DERIVATIVE | Institute of Medicinal Molecular Design, Inc. (JP) | 2009-06-24 | — | — | EP | disclosed |