Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | SOD1 | P00441 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | ENTPD5 | O75356 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15223566 | 1.00 | EP300 (0.39) | EP300SOD1OPRM1ENTPD5NR1H2 | |
| SCHEMBL16499573 | 0.85 | OPRM1 (0.45) | OPRM1ENTPD5NR1H2NR1H3OPRK1 | |
| Hypargenin C SCHEMBL18290364 | 0.80 | SOD1 (0.55) | EP300SOD1HSP90AA1KDM4EMEN1 | |
| Hypargenin C SCHEMBL31083234 | 0.80 | SOD1 (0.55) | EP300SOD1HSP90AA1KDM4EMEN1 | |
| Hypargenin C SCHEMBL13532268 | 0.80 | SOD1 (0.55) | EP300SOD1HSP90AA1KDM4EMEN1 | |
| SCHEMBL13811702 | 0.76 | SOD1 (0.46) | EP300SOD1OPRM1ENTPD5NR1H2 | |
| SCHEMBL12825588 | 0.75 | ACHE (0.44) | EP300SOD1HSP90AA1KDM4EMEN1 | |
| SCHEMBL16499584 | 0.74 | ACHE (0.35) | EP300SOD1HSP90AA1KDM4EMEN1 | |
| SCHEMBL12821396 | 0.74 | ACHE (0.35) | EP300SOD1HSP90AA1KDM4EMEN1 | |
| SCHEMBL15223565 | 0.74 | SMN1; SMN2 (0.39) | NR1H2NR1H3MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149551-A1 | OXIDIZED cis-TERPENONE AND ITS USE AS A CHEMOPROTECTIVE AND ANTI-MALARIAL AGENT | VIRGINIA COMMONWEALTH UNIVERSITY | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149551-A1 | OXIDIZED cis-TERPENONE AND ITS USE AS A CHEMOPROTECTIVE AND ANTI-MALARIAL AGENT | CYP8B1, FNTB, TOP2B | EP300 2938/4885SOD1 1355/4885OPRM1 2151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.