Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | ENTPD5 | O75356 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16499573 | 0.76 | OPRM1 (0.45) | NR1H2NR1H3OPRM1OPRD1OPRK1 | |
| SCHEMBL15223566 | 0.76 | EP300 (0.39) | SOD1NR1H2NR1H3ESR1ESR2 | |
| SCHEMBL13811695 | 0.76 | EP300 (0.39) | SOD1NR1H2NR1H3ESR1ESR2 | |
| SCHEMBL6282209 | 0.72 | SOD1 (0.66) | SOD1NR1H2NR1H3LMNACYP3A4 | |
| SCHEMBL18290367 | 0.69 | FDPS (0.50) | CYP3A4ALDH1A1MAPTHSD17B10 | |
| SCHEMBL12234042 | 0.67 | ENTPD5 (0.63) | SOD1NR1H2NR1H3CYP3A4ALDH1A1 | |
| SCHEMBL12234033 | 0.67 | ENTPD5 (0.63) | SOD1NR1H2NR1H3CYP3A4ALDH1A1 | |
| SCHEMBL12234038 | 0.67 | ENTPD5 (0.63) | SOD1NR1H2NR1H3CYP3A4ALDH1A1 | |
| SCHEMBL12234034 | 0.67 | ENTPD5 (0.63) | SOD1NR1H2NR1H3CYP3A4ALDH1A1 | |
| SCHEMBL12014319 | 0.66 | DRD2 (0.47) | ESR1ESR2HSD17B1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149551-A1 | OXIDIZED cis-TERPENONE AND ITS USE AS A CHEMOPROTECTIVE AND ANTI-MALARIAL AGENT | VIRGINIA COMMONWEALTH UNIVERSITY | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149551-A1 | OXIDIZED cis-TERPENONE AND ITS USE AS A CHEMOPROTECTIVE AND ANTI-MALARIAL AGENT | CYP8B1, FNTB, TOP2B | SOD1 1355/4885NR1H2 29/4885NR1H3 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.