Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | FADS1 | O60427 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812782 | 0.91 | NR1H4 (0.54) | NR1H4SIRT2LMNAHPGDLRRK2 | |
| SCHEMBL13812751 | 0.88 | FADS1 (0.60) | NR1H4SIRT2FADS1HPGDLRRK2 | |
| SCHEMBL13812547 | 0.88 | MEN1 (0.55) | NR1H4SIRT2LMNAFADS1MEN1 | |
| SCHEMBL13812748 | 0.88 | NR1H4 (0.55) | NR1H4SIRT2LMNAFADS1LRRK2 | |
| SCHEMBL13812761 | 0.88 | SIRT2 (0.60) | NR1H4SIRT2LMNAFADS1HPGD | |
| SCHEMBL3863657 | 0.87 | P2RX1 (0.62) | NR1H4SIRT2FADS1MEN1KMT2A | |
| SCHEMBL13812759 | 0.87 | LRRK2 (0.58) | NR1H4SIRT2FADS1LRRK2THRB | |
| SCHEMBL13812606 | 0.86 | P2RX1 (0.59) | SIRT2LMNAFADS1 | |
| SCHEMBL13812776 | 0.85 | KCNK3 (0.51) | LMNAFADS1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL13812602 | 0.85 | P2RX1 (0.58) | NR1H4SIRT2LMNAFADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |