Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812798 | 0.90 | G6PD (0.48) | G6PDCRHBPCRHR2MAPTMEN1 | |
| SCHEMBL13812670 | 0.87 | NR1H4 (0.48) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL13812763 | 0.82 | GRM5 (0.53) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL13812742 | 0.82 | KCNK3 (0.56) | MAPTKMT2AMAPK1SMN1; SMN2RAB9A | |
| SCHEMBL13812792 | 0.81 | GAA (0.60) | MAPTKMT2AALDH1A1HTTMAPK1 | |
| SCHEMBL13812801 | 0.80 | GRM5 (0.48) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL13812774 | 0.80 | SIRT2 (0.57) | MAPTKMT2AMAPK1SMN1; SMN2RAB9A | |
| SCHEMBL13812765 | 0.79 | KCNK3 (0.55) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL13812950 | 0.79 | RAB9A (0.58) | MAPTKMT2AMAPK1SMN1; SMN2RAB9A | |
| SCHEMBL13812800 | 0.79 | KDM4E (0.50) | MAPTMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |