Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812763 | 0.91 | GRM5 (0.53) | GRM5MAPTSGMS2POLBKCNK3 | |
| SCHEMBL13812800 | 0.87 | KDM4E (0.50) | GRM5MAPTSGMS2POLBKCNK3 | |
| SCHEMBL13812798 | 0.85 | G6PD (0.48) | GRM5MAPTSGMS2POLBRAB9A | |
| SCHEMBL13812560 | 0.85 | P2RX1 (0.56) | GRM5MAPTSGMS2POLBKCNK3 | |
| SCHEMBL13812931 | 0.84 | ALDH1A1 (0.49) | GRM5MAPTSGMS2POLBKDM4E | |
| SCHEMBL13812737 | 0.84 | RAB9A (0.66) | GRM5MAPTKCNK3KCNK9NPC1 | |
| SCHEMBL13812742 | 0.83 | KCNK3 (0.56) | MAPTPOLBKCNK3KCNK9KDM4E | |
| SCHEMBL13812948 | 0.82 | FADS1 (0.50) | GRM5MAPTSGMS2POLBKCNK3 | |
| SCHEMBL13812765 | 0.82 | KCNK3 (0.55) | MAPTPOLBKCNK3KCNK9KDM4E | |
| SCHEMBL13812792 | 0.82 | GAA (0.60) | MAPTPOLBKCNK3KCNK9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |