Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | MSR1 | P21757 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xanthorrizol SCHEMBL14879579 | 1.00 | SRC (0.56) | SRCPTGS1TRPA1CACNA1CPTPN1 | |
| Xanthorrizol SCHEMBL14115131 | 1.00 | SRC (0.56) | SRCPTGS1TRPA1CACNA1CPTPN1 | |
| Citronellol SCHEMBL8076836 | 0.80 | ALOX15 (0.55) | SRCPTGS1TRPA1CACNA1CPTPN1 | |
| SCHEMBL17627685 | 0.78 | SRC (0.59) | SRCPTPN1MSR1ALOX15ALDH1A1 | |
| SCHEMBL156333 | 0.78 | SRC (0.59) | SRCPTPN1MSR1ALOX15ALDH1A1 | |
| SCHEMBL309480 | 0.78 | SRC (0.59) | SRCPTPN1MSR1ALOX15ALDH1A1 | |
| SCHEMBL14283768 | 0.76 | SRC (0.66) | SRCPTPN1MSR1MAOBAPP | |
| Geraniol SCHEMBL15012445 | 0.75 | TRPA1 (0.55) | PTGS1TRPA1CACNA1CPTPN1MAOB | |
| Geraniol SCHEMBL15012448 | 0.75 | TRPA1 (0.55) | PTGS1TRPA1CACNA1CPTPN1MAOB | |
| SCHEMBL4401036 | 0.74 | TRPA1 (0.64) | PTGS1TRPA1CACNA1CALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180071180-A1 | COMPOSITION OF MATERIALS CONTAINING FLUORIDE VARNISH AND ANTIBACTERIAL AGENTS FOR PREVENTION AND TREATMENT OF DENTAL CARIES | WONKWANG UNIVERSITY CENTER FOR INDUSTRY-ACADEMY COOPERATION (KR) | 2018-03-15 | — | — | US | disclosed |
| US-20180071180-A1 | COMPOSITION OF MATERIALS CONTAINING FLUORIDE VARNISH AND ANTIBACTERIAL AGENTS FOR PREVENTION AND TREATMENT OF DENTAL CARIES | WONKWANG UNIVERSITY CENTER FOR INDUSTRY-ACADEMY COOPERATION (KR) | 2018-03-15 | — | — | US | disclosed |
| US-20090156688-A1 | SUPPRESSANT OF TOXICITY INDUCED BY CANCER CHEMOTHERAPEUTIC AGENT AND COMPOSITION OF CANCER CHEMOTHERAPEUTIC AGENT CONTAINING THE SAME | BIOCARE CO. LTD. | 2009-06-18 | — | — | US | disclosed |
| US-20090156688-A1 | SUPPRESSANT OF TOXICITY INDUCED BY CANCER CHEMOTHERAPEUTIC AGENT AND COMPOSITION OF CANCER CHEMOTHERAPEUTIC AGENT CONTAINING THE SAME | BIOCARE CO. LTD. | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156688-A1 | SUPPRESSANT OF TOXICITY INDUCED BY CANCER CHEMOTHERAPEUTIC AGENT AND COMPOSITION OF CANCER CHEMOTHERAPEUTIC AGENT CONTAINING THE SAME | CYP27A1, GOT2, UGT1A1 | SRC 1702/4885PTGS1 1462/4885TRPA1 4372/4885 |
| US-20180071180-A1 | COMPOSITION OF MATERIALS CONTAINING FLUORIDE VARNISH AND ANTIBACTERIAL AGENTS FOR PREVENTION AND TREATMENT OF DENTAL CARIES | RAB35, GANC, GALE | SRC 3533/4885PTGS1 3869/4885TRPA1 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.