Xanthorrizol

Xanthorrizol

SCHEMBL14879579

CC(C)=CCC[C@@H](C)c1ccc(C)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SRC P12931 1/20 0.56
▸ PTGS1 P23219 2/20 0.51
▸ TRPA1 O75762 1/20 0.51
▸ CACNA1C Q13936 1/20 0.51
▸ PTPN1 P18031 3/20 0.49
▸ MSR1 P21757 1/20 0.41
▸ MAOB P27338 3/20 0.38
▸ APP P05067 2/20 0.38
▸ ALOX15 P16050 3/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ IDO1 P14902 1/20 0.36
▸ GAA P10253 2/20 0.36
▸ MGAM O43451 1/20 0.36
▸ SI P14410 1/20 0.36
▸ MGAM2 Q2M2H8 1/20 0.36
▸ USP2 O75604 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthorrizol SCHEMBL13816855 1.00 SRC (0.56) SRCPTGS1TRPA1CACNA1CPTPN1
Xanthorrizol SCHEMBL14115131 1.00 SRC (0.56) SRCPTGS1TRPA1CACNA1CPTPN1
Citronellol SCHEMBL8076836 0.80 ALOX15 (0.55) SRCPTGS1TRPA1CACNA1CPTPN1
SCHEMBL156333 0.78 SRC (0.59) SRCPTPN1MSR1ALOX15ALDH1A1
SCHEMBL17627685 0.78 SRC (0.59) SRCPTPN1MSR1ALOX15ALDH1A1
SCHEMBL309480 0.78 SRC (0.59) SRCPTPN1MSR1ALOX15ALDH1A1
SCHEMBL14283768 0.76 SRC (0.66) SRCPTPN1MSR1MAOBAPP
Geraniol SCHEMBL15012445 0.75 TRPA1 (0.55) PTGS1TRPA1CACNA1CPTPN1MAOB
Geraniol SCHEMBL15012448 0.75 TRPA1 (0.55) PTGS1TRPA1CACNA1CPTPN1MAOB
SCHEMBL4401036 0.74 TRPA1 (0.64) PTGS1TRPA1CACNA1CALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119098713-A Water-based soldering flux 重庆理工大学 2024-12-10 — — CN claimed
US-20230263732-A1 COMPOSITIONS COMPRISING QUILLAJA EXTRACT AND METHODS OF PREPARATIONS AND USE THEREOF AMERICAN RIVER NUTRITION, LLC (US) 2023-08-24 — — US claimed
CN-114793892-B Primary culture method for reducing pollution and browning of yellow heart night-integrated explants 南京林业大学 2023-08-01 — — CN claimed
CN-110038057-B Nose-smoothing drop spray containing radix angelicae, preparation method thereof and application thereof in preventing and treating allergic rhinitis 刘进先 2023-07-14 — — CN claimed
US-11622947-B2 Compositions comprising quillaja extract and methods of preparations and use thereof AMERICAN RIVER NUTRITION, LLC (US) 2023-04-11 — — US claimed
EP-1765303-B2 ORAL TABLET SAFEGUARDED AGAINST ABUSE GRUENENTHAL GMBH (DE) 2022-11-23 — — EP claimed
US-11331416-B2 Method for manufacturing stent for inhibiting webbing phenomenon OSSTEM CARDIOTEC CO., LTD. (KR) 2022-05-17 — — US claimed
US-20260144799-A1 COMPOSITION COMPRISING A FIRST RAS INHIBITOR, SECOND RAS INHIBITOR AND A SHP2 INHIBITOR FOR USE IN THE TREATMENT OF CANCER Revolution Medicines, Inc. (US) 2026-05-28 — — US disclosed
EP-4747239-A1 SMALL MOLECULE PROTEIN DEGRADERS OF KRAS G12D MUTANT Merck Sharp & Dohme LLC (US) 2026-05-27 — — EP disclosed
EP-4746874-A2 SMALL MOLECULE PROTEIN DEGRADERS OF KRAS G12D MUTANT Merck Sharp & Dohme LLC (US) 2026-05-27 — — EP disclosed
US-12637445-B2 KIF18A inhibitors AMGEN INC. (US) 2026-05-26 — — US disclosed
WO-2026106912-A1 RAS INHIBITORS Revolution Medicines, Inc. (US) 2026-05-21 — — WO disclosed
EP-4743080-A2 METHODS OF TREATING A RAS RELATED DISEASE OR DISORDER Revolution Medicines, Inc. (US) 2026-05-20 — — EP disclosed
US-20220073504-A1 KIF18A INHIBITORS AMGEN INC. (US) 2022-03-10 — — US disclosed
US-20220056015-A1 KIF18A INHIBITORS AMGEN INC. (US) 2022-02-24 — — US disclosed
US-11236069-B2 KIF18A inhibitors AMGEN INC. (US) 2022-02-01 — — US disclosed
US-20180071180-A1 COMPOSITION OF MATERIALS CONTAINING FLUORIDE VARNISH AND ANTIBACTERIAL AGENTS FOR PREVENTION AND TREATMENT OF DENTAL CARIES WONKWANG UNIVERSITY CENTER FOR INDUSTRY-ACADEMY COOPERATION (KR) 2018-03-15 — — US disclosed
US-20180071180-A1 COMPOSITION OF MATERIALS CONTAINING FLUORIDE VARNISH AND ANTIBACTERIAL AGENTS FOR PREVENTION AND TREATMENT OF DENTAL CARIES WONKWANG UNIVERSITY CENTER FOR INDUSTRY-ACADEMY COOPERATION (KR) 2018-03-15 — — US disclosed
EP-2775839-A2 METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS The Regents of The University of California (US) 2014-09-17 — — EP disclosed
WO-2013059364-A2 METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-04-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220073504-A1 KIF18A INHIBITORS KIF18A, KIF18B, KIF15 SRC 1618/4885PTGS1 3058/4885TRPA1 4828/4885
US-20180071180-A1 COMPOSITION OF MATERIALS CONTAINING FLUORIDE VARNISH AND ANTIBACTERIAL AGENTS FOR PREVENTION AND TREATMENT OF DENTAL CARIES RAB35, GANC, GALE SRC 3533/4885PTGS1 3869/4885TRPA1 627/4885
US-12637445-B2 KIF18A inhibitors KIF18A, KIF18B, KIF2C SRC 297/4885PTGS1 4722/4885TRPA1 4765/4885
US-20260144799-A1 COMPOSITION COMPRISING A FIRST RAS INHIBITOR, SECOND RAS INHIBITOR AND A SHP2 INHIBITOR FOR USE IN THE TREATMENT OF CANCER PDCD1, CD274, PTPN1 SRC 50/4885PTGS1 2948/4885TRPA1 1185/4885
US-11236069-B2 KIF18A inhibitors KIF18A, KIF18B, KIF15 SRC 1506/4885PTGS1 3135/4885TRPA1 4828/4885
US-20220056015-A1 KIF18A INHIBITORS KIF18A, KIF18B, KIF15 SRC 1665/4885PTGS1 3245/4885TRPA1 4784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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