Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2146747 | 0.85 | KCNMA1 (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL3639222 | 0.80 | EGLN1 (0.45) | GPR6L3MBTL1PLCG1 | |
| SCHEMBL31394511 | 0.71 | KDM4E (0.41) | L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL30870503 | 0.68 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL22445946 | 0.64 | KCNMA1 (0.33) | L3MBTL1 | |
| SCHEMBL31146095 | 0.63 | PLCG1 (0.31) | PLCG1 | |
| Trifluoroacetic Acid SCHEMBL5259972 | 0.62 | L3MBTL1 (0.37) | L3MBTL1PLCG1 | |
| Trifluoroacetic Acid SCHEMBL30271702 | 0.62 | HAO1 (0.31) | — | |
| SCHEMBL29769325 | 0.62 | MAPK1 (0.44) | — | |
| SCHEMBL4828596 | 0.62 | MAPK1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523954-A1 | 1H-[1,2,3]TRIAZOLO[4,5-c]PYRIDINE-4-CARBONITRILE DERIVATIVES | MSD Oss B.V. (NL) | 2012-11-21 | — | — | EP | disclosed |