SCHEMBL4828596

SCHEMBL4828596

O=C(c1cccc2[nH]nnc12)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ PARP1 P09874 8/20 0.39
▸ PLA2G2D Q9UNK4 1/20 0.37
▸ PIM3 Q86V86 1/20 0.37
▸ CES1 P23141 1/20 0.35
▸ CTNNB1 P35222 1/20 0.35
▸ WNT3A P56704 1/20 0.35
▸ ACHE P22303 1/20 0.34
▸ HTT P42858 2/20 0.33
▸ JAK2 O60674 1/20 0.33
▸ TP53 P04637 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ KLK7 P49862 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29769325 1.00 MAPK1 (0.44) MAPK1KDM4EHPGDPARP1PLA2G2D
SCHEMBL10450919 0.84 PARP1 (0.39) KDM4EHPGDPARP1
SCHEMBL2188295 0.81 PARP1 (0.39) KDM4EHPGDPARP1PIM3
SCHEMBL170674 0.80 KDM4E (0.47) KDM4EHPGDPARP1
SCHEMBL4813379 0.80 PARP1 (0.38) KDM4EHPGDPARP1PIM3
SCHEMBL29453826 0.80 KDM4E (0.47) KDM4EHPGDPARP1
Phosphine SCHEMBL4726258 0.78 KDM4E (0.46) KDM4EHPGDPARP1
SCHEMBL3840407 0.78 KDM4E (0.46) KDM4EHPGDPARP1
SCHEMBL9172345 0.78 KDM4E (0.46) KDM4EHPGDPARP1
SCHEMBL1698316 0.78 PARP1 (0.56) PARP1PIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117615622-B Method for preparing solar cell with assistance of (trifluoroacetyl) benzotriazole 南开大学 2025-03-07 — — CN claimed
CN-118562565-A Stable semiconductor chip cleaning liquid and preparation method and application thereof 浙江奥首材料科技有限公司 2024-08-30 — — CN claimed
US-20240150390-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-05-09 — — US claimed
CN-117615622-A Method for preparing solar cell with assistance of (trifluoroacetyl) benzotriazole 南开大学 2024-02-27 — — CN claimed
WO-2024024935-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE HAVING ANTINEOPLASTIC EFFECT 第一三共株式会社 2024-02-01 — — WO claimed
EP-4286393-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE Daiichi Sankyo Company, Limited (JP) 2023-12-06 — — EP claimed
CN-116867795-A Novel method for producing antibody-immunostimulant conjugate 第一三共株式会社 2023-10-10 — — CN claimed
WO-2022163846-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE 第一三共株式会社 2022-08-04 — — WO claimed
EP-2985286-B1 MIDBODY OF TICAGRELOR AND PREPARATION METHOD THEREFOR, AND PREPARATION METHOD FOR TICAGRELOR JIANGSU HENGRUI MEDICINE CO (CN) 2017-10-11 — — EP claimed
US-9359366-B2 Intermediate of Ticagrelor and preparation method therefor, and preparation method for Ticagrelor JIANGSU HENGRUI MEDICINE CO., LTD. (CN) 2016-06-07 — — US claimed
US-20160052928-A1 INTERMEDIATE OF TICAGRELOR AND PREPARATION METHOD THEREFOR, AND PREPARATION METHOD FOR TICAGRELOR JIANGSU HENGRUI MEDICINE CO., LTD. (CN) 2016-02-25 — — US claimed
EP-2985286-A1 MIDBODY OF TICAGRELOR AND PREPARATION METHOD THEREFOR, AND PREPARATION METHOD FOR TICAGRELOR Jiangsu Hengrui Medicine Co. Ltd. (CN) 2016-02-17 — — EP claimed
CN-122029306-A Method for producing conductive particles and conductive powder 日本化学工业株式会社 2026-05-12 — — CN disclosed
CN-120202515-A Conductive particle, method for producing same, conductive material, and connection structure using same 日本化学工业株式会社 2025-06-24 — — CN disclosed
WO-2025079669-A1 METHOD FOR PRODUCING CONDUCTIVE PARTICLES, AND CONDUCTIVE POWDER 日本化学工業株式会社 2025-04-17 — — WO disclosed
CN-119768874-A Conductive particle, method for producing same, and conductive material 日本化学工业株式会社 2025-04-04 — — CN disclosed
US-6685995-B1 LOW VOLTAGE, WIDE TEMPERATURE RANGE DRIVING; HIGH SPEED RESPONSE CHISSO CORPORATION (JP) 2004-02-03 — — US disclosed
US-20030119751-A1 Selective neuronal nitric oxide synthase inhibitors NORTHWESTERN UNIVERSITY 2003-06-26 — — US disclosed
WO-2003000198-A2 SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS NORTHWESTERN UNIVERSITY (US) 2003-01-03 — — WO disclosed
EP-1053996-A1 ESTER COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORPORATION (JP) 2000-11-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150390-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE PAICS, COASY, CDS2 MAPK1 3524/4885KDM4E 4464/4885HPGD 1226/4885
US-20160052928-A1 INTERMEDIATE OF TICAGRELOR AND PREPARATION METHOD THEREFOR, AND PREPARATION METHOD FOR TICAGRELOR POR, CYP2C19, TKFC MAPK1 1403/4885KDM4E 3537/4885HPGD 217/4885
US-20030119751-A1 Selective neuronal nitric oxide synthase inhibitors NOS1, NOS3, NOS2 MAPK1 861/4885KDM4E 2422/4885HPGD 225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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