Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10288236 | 0.97 | ALDH1A1 (0.41) | ALDH1A1LMNANPC1RAB9ADRD2 | |
| SCHEMBL10287529 | 0.91 | SLC6A1 (0.36) | ALDH1A1LMNANPC1RAB9ADRD2 | |
| SCHEMBL10287957 | 0.91 | SIGMAR1 (0.37) | ALDH1A1LMNANPC1RAB9ADRD2 | |
| SCHEMBL13617254 | 0.90 | DRD2 (0.36) | ALDH1A1LMNANPC1RAB9ADRD2 | |
| SCHEMBL12121683 | 0.90 | SIGMAR1 (0.38) | ALDH1A1LMNANPC1RAB9ADRD2 | |
| SCHEMBL13617080 | 0.90 | DRD2 (0.36) | ALDH1A1LMNANPC1RAB9ADRD2 | |
| SCHEMBL10287605 | 0.89 | DRD2 (0.41) | DRD2DRD3CCR1DRD1HTR1A | |
| SCHEMBL10288248 | 0.89 | DRD2 (0.40) | ALDH1A1LMNANPC1RAB9ADRD2 | |
| SCHEMBL12121526 | 0.89 | SIGMAR1 (0.34) | ALDH1A1LMNANPC1RAB9ADRD2 | |
| SCHEMBL10288249 | 0.88 | CCR1 (0.36) | ALDH1A1LMNANPC1RAB9ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541365-B2 | Chemokine receptor antagonists and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-06-02 | — | — | US | disclosed |