SCHEMBL13827067

SCHEMBL13827067

BCc1cc([N+](=O)[O-])ccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.56
ALDH1A1 P00352 2/20 0.56
TSHR P16473 2/20 0.56
TP53 P04637 1/20 0.56
HPGD P15428 1/20 0.56
MAPK1 P28482 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
GAA P10253 1/20 0.55
THRB P10828 1/20 0.55
CTSB P07858 1/20 0.54
ERN1 O75460 1/20 0.51
NOX4 Q9NPH5 1/20 0.49
APP P05067 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
HSP90AA1 P07900 1/20 0.45
MEN1 O00255 1/20 0.45
CRHBP P24387 1/20 0.45
KMT2A Q03164 1/20 0.45
CRHR2 Q13324 1/20 0.45
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51277 0.85 GPR35 (0.60) GPR35ALDH1A1TSHRTP53HPGD
SCHEMBL4231830 0.83 ALDH1A1 (0.58) GPR35ALDH1A1TSHRTP53HPGD
SCHEMBL216753 0.83 GPR35 (0.58) GPR35ALDH1A1TSHRTP53HPGD
SCHEMBL786832 0.81 GAA (0.59) GPR35ALDH1A1TSHRTP53HPGD
Hydrochloric Acid SCHEMBL22773531 0.81 GPR35 (0.56) GPR35ALDH1A1TSHRTP53HPGD
SCHEMBL360284 0.81 TSHR (0.56) GPR35ALDH1A1TSHRTP53HPGD
SCHEMBL131912 0.81 GPR35 (0.56) GPR35ALDH1A1TSHRTP53HPGD
SCHEMBL786831 0.81 ALDH1A1 (0.56) GPR35ALDH1A1TSHRTP53HPGD
SCHEMBL15283303 0.81 ALDH1A1 (0.56) GPR35ALDH1A1TSHRTP53HPGD
SCHEMBL4653359 0.81 GPR35 (0.56) GPR35ALDH1A1TSHRTP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012153225-A1 IMPROVED PROCESSES FOR OBTAINING HIGH PURITY OF DRONEDARONE HYDROCHLORIDE ALEMBIC PHARMACEUTICALS LIMITED (IN) 2012-11-15 WO disclosed
WO-2007064661-A2 BIFUNCTIONAL METAL CHELATING CONJUGATES MALLINCKRODT INC. (US) 2007-06-07 WO disclosed