SCHEMBL13829447

SCHEMBL13829447

C[Si](O[Si](CCCN)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.36
HTR2A P28223 1/20 0.36
MAOA P21397 1/20 0.33
KIF11 P52732 3/20 0.32
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3418590 0.90 HRH1 (0.36) HRH1HTR2AMAOAKIF11KCNH2
SCHEMBL127764 0.88 HRH1 (0.37) HRH1HTR2AMAOAKIF11KCNH2
SCHEMBL126332 0.87 HTR2A (0.42) HRH1HTR2AMAOAKIF11KCNH2
SCHEMBL20565391 0.86 MAOA (0.35) HRH1HTR2AMAOAKIF11KCNH2
SCHEMBL12634222 0.85 HTR2A (0.33) HRH1HTR2AMAOA
SCHEMBL13100638 0.84 HTR2A (0.33) HRH1HTR2AMAOA
SCHEMBL5475785 0.83 MAOA (0.37) HRH1HTR2AMAOAKIF11KCNH2
SCHEMBL12695267 0.81 MAOA (0.32) HRH1HTR2AMAOAKIF11KCNH2
SCHEMBL26017954 0.81 HTR2A (0.30) HRH1HTR2A
SCHEMBL24433793 0.80 KIF11 (0.37) HRH1HTR2AMAOAKIF11KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120285732-A1 MULTI-LAYER WIRING BOARD TAKEUCHI KAZUMASA (JP) 2012-11-15 US disclosed