Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147211 | 0.81 | SMN1; SMN2 (0.54) | ALDH1A1MAPTTDP1MEN1THRB | |
| SCHEMBL9929149 | 0.78 | NPC1 (0.63) | ALDH1A1MAPTTDP1MEN1THRB | |
| Nitrogen SCHEMBL28644591 | 0.78 | SMN1; SMN2 (0.51) | ALDH1A1MAPTTDP1MEN1THRB | |
| SCHEMBL10086344 | 0.77 | CPS1 (0.54) | ALDH1A1MEN1KMT2AGAACYP3A4 | |
| SCHEMBL17067073 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTTDP1MEN1THRB | |
| SCHEMBL312677 | 0.77 | ALDH1A1 (0.65) | ALDH1A1MAPTTDP1MEN1THRB | |
| SCHEMBL29976235 | 0.77 | ALDH1A1 (0.65) | ALDH1A1MAPTTDP1MEN1THRB | |
| SCHEMBL148855 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTTDP1MEN1THRB | |
| SCHEMBL14608284 | 0.76 | SMN1; SMN2 (0.57) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30735974 | 0.76 | ALDH1A1 (0.62) | ALDH1A1MAPTTDP1MEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151195-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-08 | — | — | WO | disclosed |