SCHEMBL9929149

SCHEMBL9929149

COc1ccc(C(=O)c2ccc(OC)cc2N)c(N)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.63
RAB9A P51151 1/20 0.63
ALDH1A1 P00352 7/20 0.55
MAPT P10636 4/20 0.55
MEN1 O00255 2/20 0.55
THRB P10828 2/20 0.55
KMT2A Q03164 2/20 0.55
KDM4E B2RXH2 2/20 0.55
GAA P10253 2/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
MCL1 Q07820 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
HPGD P15428 5/20 0.54
CYP3A4 P08684 3/20 0.54
LMNA P02545 2/20 0.54
CYP1A2 P05177 2/20 0.54
PGR P06401 2/20 0.54
SLC6A2 P23975 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8983004 0.89 NPC1 (0.68) NPC1RAB9AALDH1A1MAPTMEN1
SCHEMBL1341206 0.87 LMNA (0.55) NPC1RAB9AALDH1A1MAPTMEN1
SCHEMBL29976235 0.86 ALDH1A1 (0.65) NPC1RAB9AALDH1A1MAPTMEN1
SCHEMBL148855 0.86 ALDH1A1 (0.53) NPC1RAB9AALDH1A1MAPTMEN1
SCHEMBL312677 0.86 ALDH1A1 (0.65) NPC1RAB9AALDH1A1MAPTMEN1
SCHEMBL147211 0.86 SMN1; SMN2 (0.54) NPC1RAB9AALDH1A1MAPTMEN1
SCHEMBL1536676 0.86 ALDH1A1 (0.69) NPC1RAB9AALDH1A1MAPTKMT2A
SCHEMBL2702904 0.86 LMNA (0.54) NPC1RAB9AALDH1A1MAPTKMT2A
SCHEMBL5617962 0.85 PARP1 (0.58) NPC1RAB9AALDH1A1MAPTMEN1
Hydrochloric Acid SCHEMBL30735974 0.85 ALDH1A1 (0.62) NPC1RAB9AALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9393720-B2 Polyimide film and process for producing polyimide film UBE INDUSTRIES, LTD. (JP) 2016-07-19 US disclosed
US-20120156482-A1 POLYMIDE FILM AND PROCESS FOR PRODUCING POLYIMIDE FILM UBE INDUSTRIES, LTD. (JP) 2012-06-21 US disclosed