SCHEMBL147211

SCHEMBL147211

COc1ccc(C(=O)O)c(N)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.54
AKR1C3 P42330 10/20 0.54
AKR1C2 P52895 10/20 0.54
ALDH1A1 P00352 4/20 0.53
KDM4E B2RXH2 3/20 0.53
MEN1 O00255 2/20 0.53
MAPT P10636 2/20 0.53
THRB P10828 2/20 0.53
KMT2A Q03164 2/20 0.53
GAA P10253 1/20 0.53
RECQL P46063 1/20 0.53
BLM P54132 1/20 0.53
MCL1 Q07820 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL28644591 0.96 SMN1; SMN2 (0.51) SMN1; SMN2AKR1C3AKR1C2ALDH1A1KDM4E
SCHEMBL31498494 0.87 ALDH1A1 (0.45) SMN1; SMN2AKR1C3AKR1C2ALDH1A1KDM4E
SCHEMBL9929149 0.86 NPC1 (0.63) SMN1; SMN2ALDH1A1KDM4EMEN1MAPT
SCHEMBL5192082 0.86 PPM1B (0.61) SMN1; SMN2AKR1C3AKR1C2ALDH1A1KDM4E
SCHEMBL312677 0.85 ALDH1A1 (0.65) SMN1; SMN2ALDH1A1KDM4EMEN1MAPT
SCHEMBL148855 0.85 ALDH1A1 (0.53) SMN1; SMN2ALDH1A1KDM4EMEN1MAPT
SCHEMBL29976235 0.85 ALDH1A1 (0.65) SMN1; SMN2ALDH1A1KDM4EMEN1MAPT
SCHEMBL27720018 0.85 SMN1; SMN2 (0.59) SMN1; SMN2AKR1C3AKR1C2ALDH1A1KDM4E
SCHEMBL29380973 0.85 SMN1; SMN2 (0.59) SMN1; SMN2AKR1C3AKR1C2ALDH1A1KDM4E
SCHEMBL221141 0.85 SMN1; SMN2 (0.59) SMN1; SMN2AKR1C3AKR1C2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 798 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12264219-B2 Conductive benzoic acid based polymer containing biomaterial for enhancement of tissue conduction in vitro and in vivo UNIVERSITY HEALTH NETWORK (CA) 2025-04-01 US claimed
CN-118546606-A Flame-retardant high-temperature-resistant heat-insulating anti-corrosion coating and preparation method thereof 河北中增智能科技有限公司 2024-08-27 CN claimed
EP-3658625-B1 CONDUCTIVE BENZOIC ACID BASED POLYMER CONTAINING BIOMATERIAL FOR ENHANCEMENT OF TISSUE CONDUCTION IN VITRO AND IN VIVO UNIV HEALTH NETWORK (CA) 2024-06-12 EP claimed
CN-113718256-B Copper etching liquid and application thereof in wafer level packaging 浙江奥首材料科技有限公司 2022-11-11 CN claimed
CN-113718256-A Copper etching liquid and application thereof in wafer level packaging 浙江奥首材料科技有限公司 2021-11-30 CN claimed
CN-110747489-B Electroreduction preparation method of intermediate of anticancer drug gefitinib and analogue thereof 湖南大学 2021-05-07 CN claimed
US-20210087336-A1 CONDUCTIVE BENZOIC ACID BASED POLYMER CONTAINING BIOMATERIAL FOR ENHANCEMENT OF TISSUE CONDUCTION IN VITRO AND IN VIVO UNIVERSITY HEALTH NETWORK (CA) 2021-03-25 US claimed
EP-3658625-A1 CONDUCTIVE BENZOIC ACID BASED POLYMER CONTAINING BIOMATERIAL FOR ENHANCEMENT OF TISSUE CONDUCTION IN VITRO AND IN VIVO University Health Network (CA) 2020-06-03 EP claimed
CN-110997810-A Electrically conductive biomaterials comprising benzoic acid based polymers for enhancing tissue conductivity in vitro and in vivo 大学健康网络 2020-04-10 CN claimed
CN-110747489-A Electroreduction preparation method of intermediate of anticancer drug gefitinib and analogue thereof 湖南大学 2020-02-04 CN claimed
WO-2019018942-A1 CONDUCTIVE BENZOIC ACID BASED POLYMER CONTAINING BIOMATERIAL FOR ENHANCEMENT OF TISSUE CONDUCTION IN VITRO AND IN VIVO UNIVERSITY HEALTH NETWORK (CA) 2019-01-31 WO claimed
CN-107383667-A A kind of formula and its processing method for adjusting seat material 徐州苏牌高温新材料有限公司 2017-11-24 CN claimed
CN-101768265-A Modified nylon and preparation method thereof UNIV SUZHOU 2010-07-07 CN claimed
US-4673740-A Preparation of substituted 2-phenyl-4H-3,1-benzoxazin-4-ones BASF AKTIENGESELLSCHAFT (DE) 1987-06-16 US claimed
US-12565511-B2 SOS1 inhibitor containing phosphorus CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2026-03-03 US disclosed
US-20260022135-A1 ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 (ENPP1) INHIBITORS AND USES THEREOF 1CBIO INC (US) 2026-01-22 US disclosed
US-12509460-B2 Methods and compositions for modulating splicing SKYHAWK THERAPEUTICS, INC. (US) 2025-12-30 US disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3954764-A NEUROLEPTIC AGENTS HOFFMANN-LA ROCHE INC. (US) 1976-05-04 US disclosed
US-3954769-A NEUROLEPTIC AGENTS HOFFMAN-LA ROCHE INC. (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509460-B2 Methods and compositions for modulating splicing SF3B1, RTCB, RBM17 SMN1; SMN2 237/4885AKR1C3 895/4885AKR1C2 1072/4885
US-20260022135-A1 ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 (ENPP1) INHIBITORS AND USES THEREOF ENPP1, ENPP3, NCEH1 SMN1; SMN2 1343/4885AKR1C3 261/4885AKR1C2 263/4885
US-12565511-B2 SOS1 inhibitor containing phosphorus SOST, SOS1, SOS2 SMN1; SMN2 1154/4885AKR1C3 2433/4885AKR1C2 1800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.