Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.63 |
| ▸ | DRD1 | P21728 | 2/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5644857 | 0.87 | DRD2 (0.59) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL723832 | 0.85 | DRD2 (0.74) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL3027352 | 0.85 | DRD2 (0.57) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL9293011 | 0.84 | MGLL (0.58) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL7470818 | 0.84 | MGLL (0.58) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL28368586 | 0.81 | DRD2 (0.68) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL2124276 | 0.81 | — | — | |
| SCHEMBL31674607 | 0.81 | DRD2 (0.68) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL11232474 | 0.81 | DRD2 (0.68) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL23754287 | 0.79 | GABRA1 (0.67) | DRD2DRD1TAAR1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825664-B2 | — | — | 2011-11-30 | — | — | JP | claimed |
| US-7781522-B2 | Curable silicone composition and cured product thereof | DOW CORNING TORAY COMPANY, LTD. (JP) | 2010-08-24 | — | — | US | claimed |
| EP-1689816-B1 | CURABLE SILICONE COMPOSITION AND CURED PRODUCT THEREOF | DOW CORNING TORAY CO LTD (JP) | 2010-07-14 | — | — | EP | claimed |
| US-20070225437-A1 | Curable Silicone Composition and Cured Product Thereof | DOW TORAY CO., LTD. (JP) | 2007-09-27 | — | — | US | claimed |
| JP-2007508345-A | — | — | 2007-04-05 | — | — | JP | claimed |
| EP-1689816-A1 | CURABLE SILICONE COMPOSITION AND CURED PRODUCT THEREOF | Dow Corning Toray Co., Ltd. (JP) | 2006-08-16 | — | — | EP | claimed |
| EP-1675848-A1 | NOVEL TRIARYLIMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-07-05 | — | — | EP | claimed |
| EP-1592389-A2 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2005-11-09 | — | — | EP | claimed |
| WO-2005044920-A1 | CURABLE SILICONE COMPOSITION AND CURED PRODUCT THEREOF | DOW CORNING TORAY CO., LTD. (JP) | 2005-05-19 | — | — | WO | claimed |
| WO-2005040153-A1 | NOVEL TRIARYLIMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-05-06 | — | — | WO | claimed |
| EP-0807114-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-11-19 | — | — | EP | claimed |
| WO-1996023791-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-08-08 | — | — | WO | claimed |
| EP-0475437-B1 | Organocyclosiloxane and method for its preparation | DOW CORNING TORAY SILICONE (JP) | 1995-11-08 | — | — | EP | claimed |
| CN-1087367-A | Structural adhesive composition with high temperature resistance | LORD CORP (US) | 1994-06-01 | — | — | CN | claimed |
| US-5290841-A | Organocyclosiloxane and method for its preparation | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1994-03-01 | — | — | US | claimed |
| US-5239085-A | Organocyclosiloxane and method for its preparation | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1993-08-24 | — | — | US | claimed |
| US-5153332-A | ORGANOCYCLOSILOXANE AND METHOD FOR ITS PREPARATION | DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) | 1992-10-06 | — | — | US | claimed |
| EP-0475437-A1 | Organocyclosiloxane and method for its preparation | Dow Corning Toray Silicone Company, Limited (JP) | 1992-03-18 | — | — | EP | claimed |
| US-5047491-A | Molding materials; waterproofing, oil repellents, antifouling agents | CHISSO CORPORATION (JP) | 1991-09-10 | — | — | US | claimed |
| EP-0355497-A2 | Polyorganosiloxane compounds | Chisso Corporation (JP) | 1990-02-28 | — | — | EP | claimed |