Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CBLB | Q13191 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245098 | 0.98 | EPHX2 (0.35) | EPHX2CBLBKMT2AATMKDM4E | |
| Hydrochloric Acid SCHEMBL3644710 | 0.97 | EPHX2 (0.35) | EPHX2CBLBKMT2AATMKDM4E | |
| Water SCHEMBL15392704 | 0.97 | EPHX2 (0.35) | EPHX2CBLBKMT2AATMKDM4E | |
| Water SCHEMBL15392456 | 0.96 | EPHX2 (0.37) | EPHX2CBLBKMT2AATMKDM4E | |
| Methacrylic Acid SCHEMBL21569269 | 0.95 | EPHX2 (0.32) | EPHX2CBLBKMT2AATMBBOX1 | |
| Methacrylic Acid SCHEMBL21569285 | 0.94 | EPHX2 (0.33) | EPHX2CBLBKMT2AATMKDM4E | |
| Water SCHEMBL15393135 | 0.94 | EPHX2 (0.39) | EPHX2CBLBKMT2AATMKDM4E | |
| Water SCHEMBL15391652 | 0.94 | CBLB (0.34) | EPHX2CBLBKMT2AATMKDM4E | |
| Water SCHEMBL4920659 | 0.94 | EPHX2 (0.32) | EPHX2BBOX1 | |
| SCHEMBL12172334 | 0.94 | EPHX2 (0.38) | EPHX2CBLBKMT2AATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12163095-B2 | Copolymers useful as water clarifiers and for water-oil separation | BAKER HUGHES OILFIELD OPERATIONS LLC (US) | 2024-12-10 | — | — | US | claimed |
| US-20240301218-A1 | Polymeric Antifouling Coating with Antimicrobial Peptides | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-09-12 | — | — | US | claimed |
| EP-3824921-B1 | BEADS FOR BLOOD PROCESSING | ASAHI KASEI MEDICAL CO LTD (JP) | 2024-08-21 | — | — | EP | claimed |
| CN-117897456-A | Polymeric antifouling coatings with antimicrobial peptides | 英属哥伦比亚大学 | 2024-04-16 | — | — | CN | claimed |
| EP-4347732-A1 | POLYMERIC ANTIFOULING COATING WITH ANTIMICROBIAL PEPTIDES | The University of British Columbia (CA) | 2024-04-10 | — | — | EP | claimed |
| US-11850345-B2 | Beads for blood processing | ASAHI KASEI MEDICAL CO., LTD. (JP) | 2023-12-26 | — | — | US | claimed |
| CN-112827478-B | Bead for blood treatment | 旭化成医疗株式会社 | 2023-06-30 | — | — | CN | claimed |
| US-11597789-B2 | Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides | WATERS TECHNOLOGIES CORPORATION (US) | 2023-03-07 | — | — | US | claimed |
| US-20230024332-A1 | Antifouling Polymeric Coating Compositions | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2023-01-26 | — | — | US | claimed |
| US-11459434-B2 | Antifouling polymeric coating compositions | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-10-04 | — | — | US | claimed |
| WO-2009126207-A1 | COMPOSITE MATERIALS CONTAINING NANOPARTICLES AND THEIR USE IN CHROMATOGRAPHY | WATERS TECHNOLOGIES CORPORATION (US) | 2009-10-15 | — | — | WO | claimed |
| EP-2101999-A1 | POROUS CARBON-HETEROATOM-SILICON HYBRID INORGANIC/ORGANIC MATERIALS FOR CHROMATOGRAPHIC SEPARATIONS AND PROCESS FOR THE PREPARATION THEREOF | Waters Technologies Corporation (US) | 2009-09-23 | — | — | EP | claimed |
| WO-2009002703-A2 | OPHTHALMIC SOLUTIONS | BAUSCH & LOMB INCORPORATED (US) | 2008-12-31 | — | — | WO | claimed |
| US-20080314767-A1 | Ophthalmic Solutions | BAUSCH & LOMB INCORPORATED (US) | 2008-12-25 | — | — | US | claimed |
| WO-2008106323-A2 | A HIGH THROUGHPUT SCREENING METHOD AND APPARATUS TO PRODUCE MODIFIED POLYMERS PARTICULARLY MEMBRANES | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2008-09-04 | — | — | WO | claimed |
| WO-2008085435-A1 | POROUS CARBON-HETEROATOM-SILICON HYBRID INORGANIC/ORGANIC MATERIALS FOR CHROMATOGRAPHIC SEPARATIONS AND PROCESS FOR THE PREPARATION THEREOF | WATERS INVESTMENTS LIMITED (US) | 2008-07-17 | — | — | WO | claimed |
| EP-1694420-A1 | METHOD FOR THE CONCENTRATION AND PURIFICATION OF BIOLOGICAL COMPOUNDS | Preentec AG (CH) | 2006-08-30 | — | — | EP | claimed |
| WO-2005058453-A1 | METHOD FOR THE CONCENTRATION AND PURIFICATION OF BIOLOGICAL COMPOUNDS | PREENTEC AG (CH) | 2005-06-30 | — | — | WO | claimed |
| WO-2004041398-A2 | POROUS INORGANIC/ORGANIC HYBRID MATERIALS AND PREPARATION THEREOF | WATERS INVESTMENTS LIMITED (US) | 2004-05-21 | — | — | WO | claimed |
| US-20030161804-A1 | Self-adhesive cationic or amphoteric free-radical polymers and cosmetic use thereof | L'OREAL (FR) | 2003-08-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240301218-A1 | Polymeric Antifouling Coating with Antimicrobial Peptides | NPPA, PDAP1, CUTA | EPHX2 4721/4885CBLB 2516/4885KMT2A 2446/4885 |
| US-20030161804-A1 | Self-adhesive cationic or amphoteric free-radical polymers and cosmetic use thereof | PARN, PCNA, F13A1 | EPHX2 1416/4885CBLB 4025/4885KMT2A 1700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.