Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.47 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23708473 | 0.75 | KMT2A (0.62) | NPC1KDM4EALDH1A1 | |
| SCHEMBL5785504 | 0.73 | SSTR3 (0.60) | NPC1RAB9AMETTL3METTL14KDM4E | |
| SCHEMBL1382509 | 0.72 | L3MBTL1 (0.55) | NPC1RAB9AMETTL3METTL14KDM4E | |
| SCHEMBL3560619 | 0.72 | IDO1 (0.58) | NPC1RAB9AMETTL3METTL14KDM4E | |
| SCHEMBL13415981 | 0.70 | MTNR1A (0.73) | NPC1RAB9AMETTL3METTL14KDM4E | |
| SCHEMBL11292300 | 0.70 | HPGD (0.55) | NPC1RAB9AKDM4ELIPGALDH1A1 | |
| SCHEMBL1383289 | 0.70 | NPC1 (0.44) | NPC1KDM4EHSD17B10HRH3CCKAR | |
| SCHEMBL19667087 | 0.69 | NPC1 (0.51) | NPC1KDM4ELIPGALDH1A1DRD2 | |
| SCHEMBL11500066 | 0.69 | HPGD (0.56) | NPC1RAB9ALIPGALDH1A1DRD2 | |
| SCHEMBL11856052 | 0.68 | LOXL2 (0.56) | METTL3METTL14KDM4EHSD17B10MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4831907-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| EP-1225894-A4 | FAB I INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-01-08 | — | — | EP | claimed |
| EP-1225894-A1 | FAB I INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-07-31 | — | — | EP | claimed |
| WO-2001026652-A1 | FAB I INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-04-19 | — | — | WO | claimed |
| EP-1225894-A4 | FAB I INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-1225894-A1 | FAB I INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001026652-A1 | FAB I INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-04-19 | — | — | WO | disclosed |