SCHEMBL13833019

SCHEMBL13833019

[O-][S+]1c2ccccc2N(c2ccccc2)c2ccc(Br)cc21

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.32
ALDH1A1 P00352 2/20 0.30
CES2 O00748 1/20 0.30
BCHE P06276 1/20 0.30
GAA P10253 1/20 0.30
CES1 P23141 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
MGLL Q99685 1/20 0.30
ALDH2 P05091 1/20 0.30
ALDH3A1 P30838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13832945 0.81 CES2 (0.30) ALDH1A1CES2BCHEGAACES1
SCHEMBL14281159 0.79 HDAC6 (0.32) ALDH1A1CES2BCHEGAACES1
SCHEMBL14281160 0.78 FAAH (0.38) ALDH1A1MGLL
SCHEMBL14281161 0.77
SCHEMBL15470443 0.76 ALDH1A1 (0.37) PGRALDH1A1CES2BCHEGAA
SCHEMBL29634622 0.76 ALDH1A1 (0.37) PGRALDH1A1CES2BCHEGAA
SCHEMBL18493730 0.74 MGLL (0.38) PGRALDH1A1CES2BCHEGAA
SCHEMBL29368871 0.74 MGLL (0.38) PGRALDH1A1CES2BCHEGAA
SCHEMBL19072064 0.74 CYP3A4 (0.31) ALDH1A1MGLL
SCHEMBL13832949 0.72 LIPG (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10177312-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2019-01-08 US disclosed
EP-2705550-B1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-07-05 EP disclosed
US-20140070146-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2014-03-13 US disclosed
US-20140070146-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2014-03-13 US disclosed
WO-2012149999-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-08 WO disclosed