Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13835948 | 0.81 | THRB (0.62) | PLA2G4BTHRBS1PR1LMNASMN1; SMN2 | |
| SCHEMBL21675973 | 0.81 | THRB (0.62) | PLA2G4BTHRBS1PR1LMNASMN1; SMN2 | |
| SCHEMBL11348102 | 0.80 | POLB (0.46) | PLA2G4BTSHRTHRBPOLBLMNA | |
| SCHEMBL13205122 | 0.80 | CYP1A2 (0.49) | TSHRTHRBPOLBLMNAMAPT | |
| SCHEMBL819519 | 0.79 | CYP1A2 (0.48) | PLA2G4BTSHRTHRBPOLBLMNA | |
| SCHEMBL819190 | 0.79 | CYP1A2 (0.48) | PLA2G4BTSHRTHRBPOLBLMNA | |
| SCHEMBL13806703 | 0.79 | THRB (0.56) | PLA2G4BTSHRTHRBHPGDS1PR1 | |
| SCHEMBL14565943 | 0.79 | TSHR (0.51) | PLA2G4BTSHRTHRBPOLBLMNA | |
| SCHEMBL21914003 | 0.78 | POLB (0.43) | PLA2G4BTSHRTHRBPOLBLMNA | |
| SCHEMBL13806706 | 0.78 | PLA2G4B (0.57) | PLA2G4BTSHRTHRBHPGDS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2711381-B1 | NOVEL COMPOUND, COMPOSITION CONTAINING SAID COMPOUND, AND CURED PRODUCT | MITSUI CHEMICALS INC (JP) | 2020-02-05 | — | — | EP | disclosed |
| EP-2710994-B1 | DENTAL MATERIAL, DENTAL MATERIAL COMPOSITION, DENTAL REPAIR MATERIAL, AND CURED PRODUCT | MITSUI CHEMICALS INC (JP) | 2018-08-01 | — | — | EP | disclosed |
| US-9511004-B2 | Dental material, dental material composition, dental restorative material, and cured product | MITSUI CHEMICALS, INC. (JP) | 2016-12-06 | — | — | US | disclosed |
| US-9504632-B2 | Compound, composition comprising the compound and cured product | MITSUI CHEMICALS, INC. (JP) | 2016-11-29 | — | — | US | disclosed |
| EP-2710994-A1 | DENTAL MATERIAL, DENTAL MATERIAL COMPOSITION, DENTAL REPAIR MATERIAL, AND CURED PRODUCT | Mitsui Chemicals, Inc. (JP) | 2014-03-26 | — | — | EP | disclosed |
| EP-2711381-A1 | NOVEL COMPOUND, COMPOSITION CONTAINING SAID COMPOUND, AND CURED PRODUCT | Mitsui Chemicals, Inc. (JP) | 2014-03-26 | — | — | EP | disclosed |
| US-20120296061-A1 | NOVEL COMPOUND, COMPOSITION COMPRISING THE COMPOUND AND CURED PRODUCT | MITSUI CHEMICALS, INC. (JP) | 2012-11-22 | — | — | US | disclosed |
| US-20120296003-A1 | DENTAL MATERIAL, DENTAL MATERIAL COMPOSITION, DENTAL RESTORATIVE MATERIAL, AND CURED PRODUCT | MITSUI CHEMICALS, INC (JP) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120296061-A1 | NOVEL COMPOUND, COMPOSITION COMPRISING THE COMPOUND AND CURED PRODUCT | GGPS1, FDFT1, FDPS | PLA2G4B 3193/4885TSHR 4869/4885THRB 4689/4885 |
| US-20120296003-A1 | DENTAL MATERIAL, DENTAL MATERIAL COMPOSITION, DENTAL RESTORATIVE MATERIAL, AND CURED PRODUCT | CAD, SEM1, REV1 | PLA2G4B 3585/4885TSHR 4854/4885THRB 3734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.