Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13836940 | 1.00 | PIK3CD (0.33) | PIK3CDGPR119CHRM4 | |
| SCHEMBL1768163 | 1.00 | PIK3CD (0.33) | PIK3CDGPR119CHRM4 | |
| SCHEMBL1768119 | 0.89 | PIK3CD (0.41) | PIK3CDGPR119 | |
| SCHEMBL1768121 | 0.85 | GPR119 (0.40) | GPR119 | |
| SCHEMBL298803 | 0.77 | PIK3CD (0.39) | PIK3CDGPR119 | |
| SCHEMBL1768128 | 0.77 | PIK3CD (0.39) | PIK3CDGPR119 | |
| SCHEMBL288648 | 0.77 | PIK3CD (0.39) | PIK3CDGPR119 | |
| SCHEMBL1768164 | 0.76 | PIK3CD (0.34) | PIK3CDGPR119CHRM4 | |
| SCHEMBL13836721 | 0.76 | PIK3CD (0.34) | PIK3CDGPR119CHRM4 | |
| SCHEMBL13836938 | 0.76 | PIK3CD (0.34) | PIK3CDGPR119CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC | 2012-11-22 | — | — | US | claimed |
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | GPR3, GPR119, GPR84 | PIK3CD 2596/4885GPR119 2/4885CHRM4 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.