Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768188 | 0.88 | GPR119 (0.56) | GPR119CYP2C9 | |
| SCHEMBL13836351 | 0.88 | GPR119 (0.47) | GPR119 | |
| SCHEMBL1768145 | 0.86 | GPR119 (0.46) | GPR119CYP2C9 | |
| SCHEMBL13836722 | 0.85 | PIK3CD (0.33) | GPR119 | |
| SCHEMBL13836940 | 0.85 | PIK3CD (0.33) | GPR119 | |
| SCHEMBL1768163 | 0.85 | PIK3CD (0.33) | GPR119 | |
| SCHEMBL288925 | 0.73 | GPR119 (0.46) | GPR119CYP2C9 | |
| SCHEMBL1768124 | 0.73 | GPR119 (0.43) | GPR119CYP2C9 | |
| SCHEMBL288068 | 0.73 | GPR119 (0.47) | GPR119CYP2C9 | |
| SCHEMBL13272803 | 0.72 | GPR119 (0.48) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC | 2012-11-22 | — | — | US | claimed |
| EP-2504342-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | Pfizer Inc. (US) | 2012-10-03 | — | — | EP | claimed |
| WO-2011061679-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC. (US) | 2011-05-26 | — | — | WO | claimed |
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC | 2012-11-22 | — | — | US | disclosed |
| EP-2504342-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | Pfizer Inc. (US) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011061679-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC. (US) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | GPR3, GPR119, GPR84 | GPR119 2/4885CYP2C9 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.