Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1384551 | 0.88 | CASR (0.46) | CASRKMT2A | |
| SCHEMBL1385867 | 0.85 | CASR (0.59) | CASRTHRBRXFP1MAPTMEN1 | |
| SCHEMBL1383520 | 0.82 | THRB (0.52) | CASRTHRBRXFP1 | |
| SCHEMBL1386100 | 0.80 | CASR (0.56) | CASRTHRBRXFP1 | |
| SCHEMBL1383335 | 0.79 | CASR (0.54) | CASRTHRBRXFP1 | |
| SCHEMBL1385344 | 0.79 | CASR (0.54) | CASRTHRBRXFP1 | |
| SCHEMBL1385847 | 0.79 | CASR (0.55) | CASRTHRBLMNA | |
| SCHEMBL1383579 | 0.79 | CASR (0.55) | CASRTHRBRXFP1 | |
| SCHEMBL3443236 | 0.79 | CASR (0.55) | CASRTHRBRXFP1MAPTMEN1 | |
| SCHEMBL1386625 | 0.78 | CASR (0.59) | CASRTHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |