Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44625 | 0.90 | MAPT (0.44) | MAPTKMT2ATHRBMEN1LMNA | |
| SCHEMBL16592815 | 0.89 | MAPT (0.43) | MAPTKMT2ATHRBMEN1LMNA | |
| SCHEMBL44935 | 0.88 | POLB (0.49) | MAPTKMT2ATHRBMEN1POLB | |
| SCHEMBL44203 | 0.88 | MAPT (0.42) | MAPTKMT2ATHRBMEN1LMNA | |
| SCHEMBL44092 | 0.87 | LMNA (0.42) | MAPTKMT2ATHRBMEN1LMNA | |
| SCHEMBL44457 | 0.86 | MAPT (0.43) | MAPTKMT2ATHRBMEN1LMNA | |
| SCHEMBL44298 | 0.86 | POLB (0.45) | MAPTKMT2ATHRBMEN1LMNA | |
| SCHEMBL43954 | 0.85 | WDR5 (0.47) | MAPTKMT2ALMNA | |
| SCHEMBL44472 | 0.85 | HTT (0.40) | MAPTKMT2ATSHR | |
| SCHEMBL44394 | 0.85 | THRB (0.46) | MAPTKMT2ATHRBMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009059162-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA ENTERPRISES LIMITED (BS) | 2009-05-07 | — | — | WO | disclosed |