Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13845148 | 0.94 | HRH3 (0.38) | — | |
| SCHEMBL13845160 | 0.76 | KDM1A (0.41) | GBA1PRKCQ | |
| SCHEMBL13845192 | 0.76 | PRKCQ (0.44) | PRKCQ | |
| SCHEMBL13845154 | 0.74 | PRKCQ (0.46) | GBA1PRKCQ | |
| SCHEMBL21358959 | 0.65 | HRH3 (0.42) | — | |
| SCHEMBL13845246 | 0.64 | TYRO3 (0.42) | GBA1PRKCQ | |
| SCHEMBL13845256 | 0.63 | HRH4 (0.38) | SLC6A2SLC6A4 | |
| SCHEMBL27987106 | 0.62 | KDM1A (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29290152 | 0.62 | MAPK8 (0.43) | — | |
| SCHEMBL3044569 | 0.61 | GBA1 (0.56) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009062059-A2 | ISOMERIC PURINONES AND 1H-IMIDAZOPYRIDINONES AS PKC-THETA INHIBITORS | PHARMACOPEIA, INC. (US) | 2009-05-14 | — | — | WO | disclosed |