Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 11/20 | 0.42 |
| ▸ | MERTK | Q12866 | 11/20 | 0.42 |
| ▸ | AXL | P30530 | 8/20 | 0.42 |
| ▸ | FLT3 | P36888 | 6/20 | 0.42 |
| ▸ | GAS6 | Q14393 | 6/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13845154 | 0.78 | PRKCQ (0.46) | TYRO3MERTKAXLFLT3GAS6 | |
| SCHEMBL13845151 | 0.76 | LMNA (0.44) | PRKCQSTK17BSTK17AGBA1 | |
| SCHEMBL13845192 | 0.73 | PRKCQ (0.44) | PRKCQ | |
| SCHEMBL14391028 | 0.71 | TYRO3 (0.54) | TYRO3MERTKAXLFLT3GAS6 | |
| SCHEMBL13845160 | 0.70 | KDM1A (0.41) | TYRO3MERTKAXLFLT3GAS6 | |
| SCHEMBL13608404 | 0.67 | JAK2 (0.42) | FLT3PRKCQ | |
| SCHEMBL12290264 | 0.67 | CHRM3 (0.54) | TYRO3MERTKAXLFLT3GAS6 | |
| SCHEMBL23500917 | 0.66 | ENPP2 (0.48) | PRKCQGBA1 | |
| SCHEMBL24083355 | 0.66 | ENPP2 (0.45) | PRKCQ | |
| SCHEMBL13845134 | 0.65 | STK17A (0.53) | PRKCQSTK17BSTK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009062059-A2 | ISOMERIC PURINONES AND 1H-IMIDAZOPYRIDINONES AS PKC-THETA INHIBITORS | PHARMACOPEIA, INC. (US) | 2009-05-14 | — | — | WO | disclosed |