Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 8/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13846218 | 0.84 | POLH (0.59) | POLHAKR1B1ALOX5MEN1KMT2A | |
| SCHEMBL13846215 | 0.80 | POLH (0.49) | POLHALOX5APPBCL9CTNNB1 | |
| SCHEMBL13846136 | 0.77 | POLH (0.66) | POLHAKR1B1ALOX5MEN1KMT2A | |
| SCHEMBL13846138 | 0.77 | AKR1B1 (0.58) | POLHAKR1B1KDM4EPOLBGAA | |
| SCHEMBL13846223 | 0.76 | POLH (0.65) | POLHAKR1B1ALOX5MEN1KMT2A | |
| SCHEMBL13846134 | 0.73 | POLH (0.58) | POLHAKR1B1ALOX5MEN1KMT2A | |
| SCHEMBL13846227 | 0.71 | AKR1B1 (0.77) | AKR1B1KDM4EPOLBGAAHSD17B10 | |
| SCHEMBL13846231 | 0.71 | POLH (0.59) | POLHAKR1B1ALOX5MEN1KMT2A | |
| SCHEMBL15928803 | 0.69 | POLH (0.72) | POLHAKR1B1ALOX5MEN1KMT2A | |
| SCHEMBL13846135 | 0.69 | MEN1 (0.57) | POLHAKR1B1ALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064485-A1 | ANTIOXIDANT FLAVONOID DERIVATIVES | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-05-22 | — | — | WO | disclosed |