Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADM2 | Q7Z4H4 | 14/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 5/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.36 |
| ▸ | CALCB | P10092 | 12/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13068979 | 0.84 | MMP13 (0.41) | ADM2CALCB | |
| SCHEMBL3034499 | 0.82 | ADM2 (0.58) | ADM2CALCRLCALCB | |
| SCHEMBL13068575 | 0.77 | ADM2 (0.32) | ADM2CALCRLCALCB | |
| SCHEMBL13846735 | 0.77 | MMP13 (0.41) | ADM2CALCRL | |
| SCHEMBL3042176 | 0.75 | ADM2 (0.51) | ADM2CALCRLCALCB | |
| SCHEMBL13069029 | 0.74 | EIF2AK3 (0.35) | — | |
| SCHEMBL550131 | 0.74 | ADM2 (0.60) | ADM2CALCRLCALCB | |
| SCHEMBL13069050 | 0.71 | SPR (0.34) | CALCRL | |
| SCHEMBL13069055 | 0.71 | ALOX15 (0.37) | CALCRL | |
| SCHEMBL3047341 | 0.70 | ADM2 (0.48) | ADM2CALCRLCALCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009065920-A2 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-28 | — | — | WO | disclosed |