Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | LY6K | Q17RY6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848277 | 0.92 | PARP14 (0.46) | HSD17B10LMNAHPGDPARP14CYP17A1 | |
| SCHEMBL13848473 | 0.88 | ALDH1A1 (0.54) | LMNAHPGDPARP14CYP17A1MAPT | |
| SCHEMBL13848266 | 0.87 | L3MBTL1 (0.54) | HPGDPARP14CYP17A1L3MBTL1ALDH1A1 | |
| SCHEMBL4068635 | 0.84 | PTGES2 (0.46) | HSD17B10HPGDPARP14CYP17A1MRGPRX1 | |
| SCHEMBL13848445 | 0.82 | MRGPRX1 (0.43) | CYP17A1MRGPRX1L3MBTL1ALOX5APFEN1 | |
| SCHEMBL13848365 | 0.81 | ALDH1A1 (0.61) | HSD17B10LMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL13848441 | 0.80 | STAT3 (0.57) | LMNAHPGDMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL13848367 | 0.80 | MEN1 (0.65) | HSD17B10LMNACYP17A1MAPTMEN1 | |
| SCHEMBL13848260 | 0.79 | ALDH1A1 (0.47) | HSD17B10LMNAPARP14PSIP1MAPT | |
| SCHEMBL13848278 | 0.77 | PARP14 (0.51) | LMNAPARP14MAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |