Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 6/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 6/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744630 | 0.85 | ENPP3 (0.42) | ENPP3ENPP1HSD11B1ADORA1ADORA3 | |
| SCHEMBL13744438 | 0.83 | CYP2A6 (0.42) | TP53MEN1RAB9AKMT2ALMNA | |
| SCHEMBL10052155 | 0.82 | ENPP3 (0.45) | ENPP3ENPP1HSD11B1ADORA1ADORA3 | |
| SCHEMBL21180807 | 0.79 | ENPP3 (0.43) | ENPP3ENPP1HSD11B1DAGLANR3C2 | |
| SCHEMBL6668389 | 0.79 | ENPP3 (0.43) | ENPP3ENPP1HSD11B1ADORA1DAGLA | |
| SCHEMBL30765909 | 0.79 | ENPP3 (0.43) | ENPP3ENPP1HSD11B1ADORA1ADORA2A | |
| SCHEMBL13744775 | 0.78 | ADORA1 (0.38) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL30003076 | 0.72 | PGR (0.40) | ENPP3ENPP1HSD11B1ADORA1ADORA3 | |
| SCHEMBL13484363 | 0.72 | CYP2D6 (0.36) | — | |
| SCHEMBL9880273 | 0.72 | S1PR1 (0.50) | ENPP3ENPP1HSD11B1DAGLAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549624-B1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | SCRIPPS RESEARCH INST (US) | 2009-05-13 | — | — | EP | disclosed |