Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668389 | 0.78 | ENPP3 (0.43) | DAGLAADORA1ENPP3ENPP1HSD11B1 | |
| SCHEMBL10052155 | 0.77 | ENPP3 (0.45) | DAGLAADORA1ADORA3ADORA2AENPP3 | |
| SCHEMBL21180807 | 0.74 | ENPP3 (0.43) | DAGLAENPP3ENPP1HSD11B1TDP1 | |
| SCHEMBL30765909 | 0.74 | ENPP3 (0.43) | DAGLAADORA1ADORA2AENPP3ENPP1 | |
| SCHEMBL9441037 | 0.73 | MAOA (0.45) | ADORA3SMOLMNASMN1; SMN2 | |
| SCHEMBL13848629 | 0.72 | ENPP3 (0.44) | DAGLAADORA1ADORA3ADORA2AENPP3 | |
| SCHEMBL4737344 | 0.72 | MAPT (0.49) | TDP1ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL13744630 | 0.70 | ENPP3 (0.42) | DAGLAADORA1ADORA3ADORA2AENPP3 | |
| SCHEMBL5296166 | 0.67 | DAGLA (0.57) | DAGLAENPP3ENPP1HSD11B1SMO | |
| SCHEMBL4806377 | 0.67 | PTGS2 (0.69) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653613-B1 | 1,3-DI-SUBSTITUTED KETENE COMPOUND AND APPLICATION THEREOF | BEBETTER MED INC (CN) | 2022-11-16 | — | — | EP | disclosed |