Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 7/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 5/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10052155 | 0.85 | ENPP3 (0.45) | ENPP3ENPP1HSD11B1MEN1KMT2A | |
| SCHEMBL21180807 | 0.82 | ENPP3 (0.43) | ENPP3ENPP1HSD11B1MEN1KMT2A | |
| SCHEMBL6668389 | 0.82 | ENPP3 (0.43) | ENPP3ENPP1HSD11B1MEN1KMT2A | |
| SCHEMBL13848629 | 0.79 | ENPP3 (0.44) | ENPP3ENPP1HSD11B1MEN1KMT2A | |
| SCHEMBL13744630 | 0.77 | ENPP3 (0.42) | ENPP3ENPP1HSD11B1MEN1KMT2A | |
| SCHEMBL30003076 | 0.74 | PGR (0.40) | ENPP3ENPP1HSD11B1ADORA2AADORA1 | |
| SCHEMBL31558543 | 0.74 | HSD11B1 (0.35) | ENPP3ENPP1HSD11B1MEN1KMT2A | |
| Benzene SCHEMBL7220483 | 0.73 | — | — | |
| SCHEMBL2265105 | 0.71 | ENPP3 (0.68) | ENPP3ENPP1HSD11B1MEN1KMT2A | |
| SCHEMBL8119166 | 0.71 | LTA4H (0.54) | ENPP3ENPP1HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |