Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10090133 | 0.86 | BRD4 (0.48) | BRD4BCHEHDAC3HDAC4HDAC1 | |
| SCHEMBL1609731 | 0.82 | HDAC3 (0.45) | BRD4BCHEHDAC3HDAC4HDAC1 | |
| SCHEMBL11752297 | 0.81 | SIRT2 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4952678 | 0.81 | SIRT2 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL17742912 | 0.81 | CYP3A4 (0.48) | BRD4BCHETPSAB1TPSD1TPSG1 | |
| SCHEMBL2216539 | 0.80 | SIRT2 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10090132 | 0.80 | BCHE (0.45) | BRD4BCHEHDAC3HDAC4HDAC1 | |
| SCHEMBL17763229 | 0.80 | BRD4 (0.55) | BRD4BCHEASAH1DRD2 | |
| SCHEMBL13782023 | 0.79 | CYP4Z1 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29964193 | 0.78 | BCHE (0.49) | BRD4BCHENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124832-A1 | OLIGOAMINE COMPOUNDS AND DERIVATIVES THEREOF FOR CANCER THERAPY | PROGEN PHARMACEUTICALS, INC. (US) | 2009-05-14 | — | — | US | disclosed |
| US-20090124832-A1 | OLIGOAMINE COMPOUNDS AND DERIVATIVES THEREOF FOR CANCER THERAPY | PROGEN PHARMACEUTICALS, INC. (US) | 2009-05-14 | — | — | US | disclosed |
| US-7491849-B2 | Oligoamine compounds and derivatives thereof for cancer therapy | PROGEN PHARMACEUTICALS, INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-7491849-B2 | Oligoamine compounds and derivatives thereof for cancer therapy | PROGEN PHARMACEUTICALS, INC. (US) | 2009-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124832-A1 | OLIGOAMINE COMPOUNDS AND DERIVATIVES THEREOF FOR CANCER THERAPY | THOP1, OAT, DUT | BRD4 900/4885BCHE 2657/4885HDAC3 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.