Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | DDX3X | O00571 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | BLK | P51451 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5922913 | 0.85 | CYP1A2 (0.54) | ALDH1A1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL13856226 | 0.84 | SMN1; SMN2 (0.50) | ALDH1A1RAB9ASMN1; SMN2KMT2ACRHBP | |
| SCHEMBL5923163 | 0.81 | RAB9A (0.52) | ALDH1A1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL5923530 | 0.80 | RAB9A (0.44) | NR4A1ALDH1A1RAB9AKMT2APOLB | |
| SCHEMBL14861785 | 0.80 | GAA (0.46) | ALDH1A1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL5923055 | 0.78 | RAB9A (0.49) | ALDH1A1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL5923599 | 0.78 | ALDH1A1 (0.49) | ALDH1A1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL5923308 | 0.78 | RAB9A (0.48) | ALDH1A1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL20057674 | 0.77 | DDX3X (0.58) | NR4A1ALDH1A1RAB9ADDX3XSMN1; SMN2 | |
| SCHEMBL5923368 | 0.76 | CRHBP (0.50) | ALDH1A1RAB9ASMN1; SMN2KMT2ACRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | BCL2, BAX, BAD | NR4A1 4082/4885ALDH1A1 3724/4885RAB9A 3519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.