Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13856217 | 0.85 | NR4A1 (0.57) | CYP1A2CYP2D6POLBCRHBPCRHR2 | |
| SCHEMBL6422898 | 0.85 | HSD17B10 (0.62) | CYP1A2CYP2D6CYP3A4CYP2C19RAB9A | |
| SCHEMBL5923163 | 0.84 | RAB9A (0.52) | POLBCRHBPCRHR2RAB9ASMN1; SMN2 | |
| SCHEMBL14861785 | 0.82 | GAA (0.46) | POLBRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL5923530 | 0.82 | RAB9A (0.44) | CYP1A2CYP2D6POLBCRHBPCRHR2 | |
| SCHEMBL5923368 | 0.82 | CRHBP (0.50) | CRHBPCRHR2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5923599 | 0.80 | ALDH1A1 (0.49) | POLBRAB9ASMN1; SMN2NPC1MAPK1 | |
| SCHEMBL5923055 | 0.80 | RAB9A (0.49) | CYP1A2POLBCYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL5923308 | 0.80 | RAB9A (0.48) | CYP1A2POLBCYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL13302660 | 0.80 | NPSR1 (0.57) | CYP1A2CYP2D6POLBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160374997-A1 | ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2016-12-29 | — | — | US | disclosed |
| US-20160220510-A1 | ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2016-08-04 | — | — | US | disclosed |
| US-20060100225-A1 | Heteroaryl guanidines; inhibitors of viral replication | ACHILLION PHARMACEUTICALS, INC. | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160374997-A1 | ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS | AARS1, EPRS1, EEF1G | CYP1A2 3382/4885CYP2D6 2559/4885POLB 1612/4885 |
| US-20160220510-A1 | ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS | AARS1, EPRS1, EEF1G | CYP1A2 3382/4885CYP2D6 2559/4885POLB 1612/4885 |
| US-20060100225-A1 | Heteroaryl guanidines; inhibitors of viral replication | PIGS, GUCY1A1, GUCY1B1 | CYP1A2 295/4885CYP2D6 562/4885POLB 2292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.