Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CENPE | Q02224 | 6/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ESRRB | O95718 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386801 | 0.91 | SIGMAR1 (0.32) | ESRRGTP53MAPTSIGMAR1MEN1 | |
| SCHEMBL1386433 | 0.91 | TRPV1 (0.35) | ESRRGTP53MAPTCENPEHDAC11 | |
| SCHEMBL1386237 | 0.90 | ESRRG (0.34) | ESRRGTP53MAPTHDAC11HDAC8 | |
| SCHEMBL1386968 | 0.89 | MEN1 (0.37) | ESRRGTP53MAPTNR1H4MEN1 | |
| SCHEMBL1397545 | 0.87 | CCR9 (0.34) | TP53MAPTSIGMAR1MEN1ALDH1A1 | |
| SCHEMBL1385936 | 0.86 | LPAR1 (0.37) | ESRRGTP53MAPT | |
| SCHEMBL5529652 | 0.84 | ESRRG (0.34) | ESRRGTP53MAPTNR1H4SIGMAR1 | |
| SCHEMBL5530770 | 0.83 | GRM5 (0.38) | ESRRGTP53MAPTNR1H4SIGMAR1 | |
| SCHEMBL5530101 | 0.82 | TRPM8 (0.34) | ESRRGCENPE | |
| SCHEMBL5529262 | 0.81 | HDAC6 (0.35) | ESRRGTP53MAPTNR1H4CENPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4787254-B2 | — | — | 2011-10-05 | — | — | JP | claimed |