Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 2/20 | 0.34 |
| ▸ | ESRRG | P62508 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | CENPE | Q02224 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386237 | 0.95 | ESRRG (0.34) | ESRRGTP53MAPTLPAR1LPAR5 | |
| SCHEMBL1385947 | 0.91 | ESRRG (0.36) | ESRRGTP53MAPTHDAC8HDAC6 | |
| SCHEMBL1386968 | 0.89 | MEN1 (0.37) | ESRRGTP53MAPTLPAR1LPAR5 | |
| SCHEMBL5529673 | 0.85 | CDK8 (0.35) | TRPV1CDK8ESRRGRAPGEF3RAPGEF4 | |
| SCHEMBL5537737 | 0.85 | GRM5 (0.35) | TRPV1CDK8ESRRGRAPGEF3RAPGEF4 | |
| SCHEMBL5526900 | 0.83 | KDM4A (0.39) | TRPV1CDK8TP53MAPTTRPM8 | |
| SCHEMBL1386801 | 0.83 | SIGMAR1 (0.32) | ESRRGTP53MAPTCENPE | |
| SCHEMBL1385936 | 0.83 | LPAR1 (0.37) | ESRRGTP53MAPTLPAR1LPAR5 | |
| SCHEMBL12520972 | 0.81 | TRPM8 (0.37) | ESRRGTP53MAPTRAPGEF3RAPGEF4 | |
| SCHEMBL5528436 | 0.80 | TRPM8 (0.34) | CDK8TRPM8KDM4AKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4787254-B2 | — | — | 2011-10-05 | — | — | JP | claimed |