Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | CENPE | Q02224 | 2/20 | 0.31 |
| ▸ | ESRRG | P62508 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385947 | 0.91 | ESRRG (0.36) | SIGMAR1MEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL1397545 | 0.84 | CCR9 (0.34) | SIGMAR1MEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL1386433 | 0.83 | TRPV1 (0.35) | TP53MAPTCENPEESRRG | |
| SCHEMBL1386856 | 0.83 | PPARG (0.35) | PPARGPPARDPPARASLC6A4 | |
| SCHEMBL1386237 | 0.81 | ESRRG (0.34) | TP53MAPTESRRG | |
| SCHEMBL1386968 | 0.81 | MEN1 (0.37) | MEN1TP53CYP1A2MAPTCYP2C19 | |
| SCHEMBL1385936 | 0.78 | LPAR1 (0.37) | TP53MAPTPPARGPPARDPPARA | |
| SCHEMBL1397829 | 0.76 | CCR9 (0.36) | MAOB | |
| SCHEMBL5529652 | 0.76 | ESRRG (0.34) | SIGMAR1MEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL1397553 | 0.75 | TRPM8 (0.35) | MEN1KMT2APPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4787254-B2 | — | — | 2011-10-05 | — | — | JP | claimed |