Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KYNU | Q16719 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383618 | 0.87 | ALOX5 (0.47) | PDK1MEN1KMT2AALOX5ALDH1A1 | |
| SCHEMBL1386304 | 0.84 | SLC16A3 (0.41) | PDK1MEN1KMT2AMKNK1SLC16A3 | |
| SCHEMBL3442836 | 0.84 | ALOX5 (0.40) | PDK1MEN1KMT2AALOX5ALDH1A1 | |
| SCHEMBL3946482 | 0.84 | ALOX5 (0.39) | PDK1MEN1KMT2AMKNK1ALOX5 | |
| SCHEMBL5711059 | 0.81 | KCNK3 (0.45) | KMT2AALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL1384100 | 0.80 | FYN (0.39) | PDK1MEN1KMT2AMKNK1SLC16A3 | |
| SCHEMBL20827805 | 0.80 | PDK1 (0.40) | PDK1KMT2AMKNK1 | |
| SCHEMBL1383959 | 0.78 | CASR (0.49) | MEN1KMT2AALOX5ALDH1A1KDM4E | |
| SCHEMBL1383842 | 0.77 | ALOX5 (0.42) | PDK1MEN1KMT2AALOX5ALDH1A1 | |
| SCHEMBL1386195 | 0.77 | AOC3 (0.38) | MEN1KMT2AALOX5ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |