Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386304 | 0.88 | SLC16A3 (0.41) | MEN1KMT2ACLK4HDAC3HDAC1 | |
| SCHEMBL3945243 | 0.87 | FYN (0.39) | FYNCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL1386196 | 0.80 | PDK1 (0.43) | CYP1A2CYP2C19HSD17B10HPGDTSHR | |
| SCHEMBL3442903 | 0.75 | KDM4C (0.53) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL3952000 | 0.75 | SLC16A3 (0.40) | MEN1KMT2ACLK4HDAC3HDAC1 | |
| SCHEMBL1383227 | 0.73 | ALDH1A1 (0.42) | CYP1A2CYP3A4HSD17B10HPGDUSP2 | |
| SCHEMBL3942976 | 0.72 | CASR (0.41) | CYP3A4CYP2D6MAPTMEN1KMT2A | |
| SCHEMBL3443587 | 0.71 | ALDH1A1 (0.58) | CYP1A2CYP3A4CYP2C19HSD17B10HPGD | |
| SCHEMBL3946248 | 0.70 | NPY5R (0.42) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL1383618 | 0.69 | ALOX5 (0.47) | CYP1A2CYP3A4HSD17B10HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |