SCHEMBL418120

SCHEMBL418120

Nc1ccc2c(c1)Oc1cc(N)ccc1C2(O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 4/20 0.42
FTO Q9C0B1 2/20 0.41
CHEK1 O14757 1/20 0.40
PRKD3 O94806 1/20 0.40
MAP4K4 O95819 1/20 0.40
RET P07949 1/20 0.40
MET P08581 1/20 0.40
PDGFRA P16234 1/20 0.40
FLT1 P17948 1/20 0.40
LTK P29376 1/20 0.40
PRKX P51817 1/20 0.40
NEK2 P51955 1/20 0.40
JAK3 P52333 1/20 0.40
BTK Q06187 1/20 0.40
MAP4K2 Q12851 1/20 0.40
DYRK1A Q13627 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30187261 0.82 MAPT (0.44) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL3471424 0.82 MAPT (0.44) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL179720 0.81 FTO (0.49) MAPTMEN1KMT2AALDH1A1FTO
SCHEMBL22050403 0.79 MEN1 (0.42) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL29722 0.77 CHRM3 (0.46) MEN1KMT2AP2RX4P2RX1P2RX3
SCHEMBL13458772 0.76 FTO (0.40) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL14022367 0.76 HPGD (0.39) MAPTMEN1KMT2AALDH1A1FTO
SCHEMBL3472059 0.76 PDK2 (0.43) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL22050411 0.76 HSD17B10 (0.42) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL30398085 0.76 PDK2 (0.43) MAPTMEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230375558-A1 Methods for Using Collagen Hybridizing Peptides to Determine Collagen Content 3HELIX, INC. (US) 2023-11-23 US disclosed
US-20230364271-A1 METHODS AND COMPOSITIONS FOR INCREASING UPTAKE, INTERNALIZATION, AND/OR RETENTION OF SMALL MOLECULE LIGANDS CORNELL UNIVERSITY 2023-11-16 US disclosed
CN-116888143-A Method for determining collagen content by using collagen hybrid peptide 3螺旋有限公司 2023-10-13 CN disclosed
EP-4221763-A1 METHODS AND COMPOSITIONS FOR INCREASING UPTAKE, INTERNALIZATION, AND/OR RETENTION OF SMALL MOLECULE LIGANDS Cornell University (US) 2023-08-09 EP disclosed
EP-4217382-A1 METHODS FOR USING COLLAGEN HYBRIDIZING PEPTIDES TO DETERMINE COLLAGEN CONTENT 3Helix, Inc. (US) 2023-08-02 EP disclosed
WO-2022072292-A1 METHODS AND COMPOSITIONS FOR INCREASING UPTAKE, INTERNALIZATION, AND/OR RETENTION OF SMALL MOLECULE LIGANDS CORNELL UNIVERSITY (US) 2022-04-07 WO disclosed
US-10941211-B2 Anti-GCC antibody molecules and related compositions and methods MILLENNIUM PHARMACEUTICALS, INC. (US) 2021-03-09 US disclosed
EP-2490720-B1 ANTI-GCC ANTIBODY MOLECULES AND RELATED COMPOSITIONS AND METHODS MILLENNIUM PHARM INC (US) 2020-02-12 EP disclosed
EP-3520816-A2 ANTI-GCC ANTIBODY MOLECULES AND RELATED COMPOSITIONS AND METHODS Millennium Pharmaceuticals, Inc. (US) 2019-08-07 EP disclosed
EP-2841575-B1 ANTI-GCC ANTIBODY MOLECULES AND USE OF SAME TO TEST FOR SUSCEPTIBILITY TO GCC-TARGETED THERAPY MILLENNIUM PHARM INC (US) 2019-06-26 EP disclosed
US-4220450-A Chemically induced fluorescence immunoassay SYVA COMPANY (US) 1980-09-02 US disclosed
US-4199559-A DETERMINING THE PRESENCE OR AMOUNT OF A LIGAND OR ANTIBODIES SYVA COMPANY (US) 1980-04-22 US disclosed
US-4174384-A Fluorescence quenching with immunological pairs in immunoassays SYVA COMPANY (US) 1979-11-13 US disclosed
US-4161515-A DETECTING ANTILIGAND WITH LIGAND-ANALOG FLUORESCER SYVA COMPANY (US) 1979-07-17 US disclosed
US-4160016-A Receptor fluorescent immunoassay SYVA COMPANY (US) 1979-07-03 US disclosed
US-4130462-A Receptor steric hindrance immunoassay for receptor determination SYVA COMPANY (US) 1978-12-19 US disclosed
US-3998943-A Double receptor fluorescent immunoassay SYVA COMPANY (US) 1976-12-21 US disclosed
US-3996345-A Fluorescence quenching with immunological pairs in immunoassays SYVA COMPANY (US) 1976-12-07 US disclosed
US-3939350-A Fluorescent immunoassay employing total reflection for activation BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1976-02-17 US disclosed
US-3935074-A Antibody steric hindrance immunoassay with two antibodies SYVA COMPANY (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10941211-B2 Anti-GCC antibody molecules and related compositions and methods CD2BP2, UACA, COPG2 MAPT 3294/4885MEN1 2481/4885KMT2A 2642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.