Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13886265 | 0.83 | BRD4 (0.39) | BRD4L3MBTL1LMNAHTTNPSR1 | |
| SCHEMBL14664041 | 0.72 | SLC6A2 (0.51) | HTT | |
| SCHEMBL29192390 | 0.72 | BRD4 (0.38) | BRD4L3MBTL1BACE1MAPTNPC1 | |
| SCHEMBL29192329 | 0.70 | BRD4 (0.40) | BRD4MAPK1EPHX2SIRT2ATM | |
| SCHEMBL6830859 | 0.67 | LMNA (0.40) | L3MBTL1LMNAHTTNPSR1BACE1 | |
| SCHEMBL4592268 | 0.67 | ALOX15 (0.38) | BRD4L3MBTL1POLBMAPTNPC1 | |
| SCHEMBL28739869 | 0.67 | L3MBTL1 (0.50) | L3MBTL1LMNAHTTNPSR1BACE1 | |
| SCHEMBL16669626 | 0.67 | BRD4 (0.48) | BRD4LMNAHTTMAPK1MAPT | |
| SCHEMBL6773172 | 0.65 | BRD4 (0.42) | BRD4HTTMAPK1POLBMAPT | |
| SCHEMBL5837737 | 0.65 | BRD4 (0.42) | BRD4HTTMAPK1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524883-B2 | Eponemycin and epoxomicin analogs and uses thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |