Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038616 | 0.80 | ALDH1A1 (0.35) | LMNAMMP8MEN1KMT2AMAPT | |
| SCHEMBL9680001 | 0.79 | GRIN2B (0.45) | L3MBTL1MEN1KMT2AMAPTCYP2D6 | |
| SCHEMBL6919722 | 0.79 | TP53 (0.38) | CYP3A4MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL28739869 | 0.75 | L3MBTL1 (0.50) | LMNAHTTNPSR1L3MBTL1MMP8 | |
| SCHEMBL6829064 | 0.72 | CYP3A4 (0.40) | LMNAHTTNPSR1L3MBTL1HSD11B1 | |
| SCHEMBL414249 | 0.71 | SLC6A2 (0.56) | HTTHRH3CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL10956783 | 0.71 | SLC6A2 (0.56) | HTTHRH3CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL440476 | 0.71 | SLC6A2 (0.56) | HTTHRH3CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL5334825 | 0.70 | ALDH1A1 (0.40) | LMNANPSR1L3MBTL1MAPTHDAC9 | |
| SCHEMBL3733923 | 0.70 | HDAC9 (0.38) | MMP8MAPTHDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096774-A1 | ACYL ISOINDOLINE DERIVATIVES AND ACYL ISOQUINOLINE DERIVATIVES AS ANTI-VIRAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |